Acute arterial thrombosis of the lower extremity. Its natural history contrasted with arterial embolism

Archives of Surgery
R P Cambria, W M Abbott


We compared a group of 52 patients with acute lower extremity ischemia secondary to arterial thrombosis with a series of 220 patients with peripheral embolism who were seen at the Massachusetts General Hospital, Boston, from 1967 through 1980. The conditions of patients with arterial thrombosis were misdiagnosed as acute embolism at a rate of 20%. Mortality in the patients with embolism was significantly higher. While patients with acute embolism were routinely treated with embolectomy, two thirds of the patients with thrombotic occlusion required surgery during their initial hospitalization for ongoing severe ischemia. More than half of these operations were carried out as emergency procedures. Limb salvage in surgically treated patients with arterial thrombosis was inferior to that seen with embolism. Early revascularization for acute thrombosis was carried out with a 30-day patency rate of 82%. While the mortality associated with acute thrombosis was significantly lower than that seen with peripheral embolism, the risk of major amputation was 35%. There should be no reluctance to proceed with indicated vascular reconstruction in the setting of acute limb ischemia secondary to arterial thrombosis.


Jul 1, 1991·Annals of Surgery·R P CambriaW M Abbott
Aug 26, 1989·BMJ : British Medical Journal·W B Campbell, T R Magee
Sep 30, 2003·Journal of Vascular and Interventional Radiology : JVIR·UNKNOWN Working Party on Thrombolysis in the Management of Limb Ischemia
Mar 20, 2010·Journal of the American Academy of Nurse Practitioners·Laura Bourdeanu, Thehang Luu
Nov 1, 1991·The Journal of Surgical Research·N A ChoudhuryH Muro
Jan 1, 1987·The Australian and New Zealand Journal of Surgery·R Englund, H R Magee
Aug 1, 1989·European Journal of Vascular Surgery·A E ClasonC V Ruckley
Aug 1, 1987·European Journal of Vascular Surgery·E B DregelidA Trippestad
Aug 1, 1990·European Journal of Vascular Surgery·J J EarnshawG S Makin
Sep 10, 1999·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·D J BowlerD Bouchier-Hayes
Aug 16, 2000·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·P DesgrangesJ P Becquemin
Feb 1, 1996·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C LjungmanH O Adami
Feb 20, 2004·Current Surgery·Ronald B JohnstonAlvin M Cotlar
Jan 1, 1991·Annals of Vascular Surgery·J L Mills, J M Porter
Mar 21, 1998·The British Journal of Surgery·B D BraithwaiteJ J Earnshaw
Sep 1, 1987·The British Journal of Surgery·L E JivegårdT Scherstén
Mar 1, 1991·The British Journal of Surgery·J J Earnshaw
Jun 11, 2002·Journal of Interventional Cardiology·J R Laird
Aug 26, 1989·BMJ : British Medical Journal·C H Bullough
Aug 10, 2004·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·David E AllieCraig M Walker
May 16, 1991·The New England Journal of Medicine·M Odeh
Nov 20, 1998·Chest·M R Jackson, G P Clagett

❮ Previous
Next ❯

Related Concepts

Related Feeds


Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.