Acute bovine laminitis: a new induction model using alimentary oligofructose overload

Journal of Dairy Science
M B ThoefnerP H Andersen

Abstract

Twelve dairy heifers were used to examine the clinical response of an alimentary oligofructose overload. Six animals were divided into 3 subgroups, and each was given a bolus dose of 13, 17, or 21 g/kg of oligofructose orally. The control group (n = 6) was sham-treated with tap water. Signs of lameness, cardiovascular function, and gastrointestinal function were monitored every 6 h during development of rumen acidosis. The heifers were euthanized 48 and 72 h after administration of oligofructose. All animals given oligofructose developed depression, anorexia, and diarrhea 9 to 39 h after receiving oligofructose. By 33 to 45 h after treatment, the feces returned to normal consistency and the heifers began eating again. Animals given oligofructose developed transient fever, severe metabolic acidosis, and moderate dehydration, which were alleviated by supportive therapy. Four of 6 animals given oligofructose displayed clinical signs of laminitis starting 39 to 45 h after receiving oligofructose and lasting until euthanasia. The lameness was obvious, but could easily be overlooked by the untrained eye, because the heifers continued to stand and walk, and did not interrupt their eating behavior. No positive pain reactions or lamenes...Continue Reading

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Nov 21, 2017·Journal of Dairy Science·A J HeinrichsC M Jones
Sep 1, 2017·Tropical Animal Health and Production·M B SadiqWan Mastura Shaik Mossadeq
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Aug 9, 2020·Frontiers in Veterinary Science·Jiafeng DingHongbin Wang
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Related Concepts

Oligofructose
Metabolic Acidosis
Acute Disease
Anorexia
Bos indicus
Cattle Diseases
Water Stress
Diarrhea
Foot Diseases
Inflammation

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