PMID: 8474635Mar 1, 1993Paper

Acute cocaine treatment decreases oxytocin levels in the rat hippocampus

Neuropeptides
J M JohnsC A Pedersen

Abstract

We examined the effects of an acute cocaine treatment on oxytocin levels in the whole hippocampus, ventral tegmental area (VTA) and amygdala in ovariectomized rats pretreated with 10 micrograms estradiol benzoate. Cocaine treatment significantly reduced oxytocin levels both in picograms/area and picograms/mg wet weight in the hippocampus but had no significant effect on levels in the VTA and amygdala. These data represent the first evidence for the reduction of oxytocin levels as a result of an acute cocaine treatment.

References

Jun 12, 1992·Annals of the New York Academy of Sciences·C F FerrisT R Insel
Sep 12, 1985·The New England Journal of Medicine·I J ChasnoffK A Burns
Jun 1, 1967·Journal of Comparative and Physiological Psychology·D P KimbleC W Hendrickson
May 7, 1982·Science·C A PedersenA J Prange
May 1, 1994·Developmental Psychobiology·J M JohnsB A McMillen

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Citations

Mar 1, 1997·Pharmacology, Biochemistry, and Behavior·S PetruzziG Laviola
Dec 27, 2011·Hormones and Behavior·Iain S McGregor, Michael T Bowen
Jan 21, 2020·Journal of Behavioral Addictions·Mi Ran ChoiDai-Jin Kim
Feb 19, 2021·Pharmacology & Therapeutics·Xiaohang CheChunfu Wu
Mar 7, 2021·International Journal of Molecular Sciences·Carmen Ferrer-PérezMarta Rodríguez-Arias

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