PMID: 16613198Apr 15, 2006Paper

Acute coronary syndrome risk management

Nihon rinsho. Japanese journal of clinical medicine
Ken Shimamoto, Masatoshi Kawana

Abstract

Coronary atherosclerosis begins in early life and progresses through adulthood, exacerbated by various risk factors. The past decade has witnessed an increasing recognition that endothelial dysfunction and inflammatory mechanisms play a central role in the pathogenesis of atherosclerosis and acute coronary syndrome (ACS). Advances in the management of patients with ACS have evolved dramatically. Recently the concept of interventional cardiology expand beyond mechanical revascularization to embrace preventive interventions that forestall future cardiac and vascular events. The pleiotropic effect of preventive agents contributes to early and significant risk reduction in high-risk patients and also after being suffered from ACS.

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