Acute effect of MitraClip implantation on mitral valve geometry in patients with functional mitral regurgitation: insights from three-dimensional transoesophageal echocardiography

EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Ibtihal Al AmriVictoria Delgado

Abstract

Our aim was to evaluate the acute effects of transcatheter edge-to-edge mitral valve repair using the MitraClip device on mitral valve geometry in patients with functional mitral regurgitation (FMR). Forty-two patients (age 73 years [IQ range 66.1-78.0], 55% men, 62% ischaemic FMR) with moderate-to-severe and severe FMR treated with the MitraClip were included. Three-dimensional transoesophageal echocardiography was performed prior to and immediately after MitraClip implantation. Acute changes of mitral annular and leaflet geometry were assessed with dedicated mitral modelling software. FMR less than moderate grade was achieved in 36 (86%) patients. After MitraClip implantation, the mitral annulus became more elliptical (ellipticity from 122±17% to 129±18%; p=0.04) with a non-significant reduction in anteroposterior diameter (33±6 to 32±5 mm, p=0.08). The coaptation area increased from 350 mm2 (IQ range 289-493 mm2) to 434 mm2 (IQ range 328-523 mm2, p=0.008). In particular, a larger part of the anterior mitral leaflet was included in the coaptation, leaving a smaller exposed anterior leaflet length of the A2 segment (from 27±6 mm to 25±5 mm, p<0.05) while the exposed length of the posterior leaflet (P2 level) remained unchanged...Continue Reading

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Nov 5, 2014·European Heart Journal Cardiovascular Imaging·Philippe DebonnaireVictoria Delgado

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Citations

Dec 16, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mehmet Cilingiroglu, Konstantinos Marmagkiolis
Jul 26, 2019·Journal of Cardiovascular Medicine·Sara CiminoLuciano Agati
Jul 27, 2021·Circulation. Cardiovascular Interventions·Felix KreidelRalph Stephan von Bardeleben

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