PMID: 11907924Mar 23, 2002Paper

Acute effects of a surgical menopause on serum concentrations of lipoprotein(a)

Climacteric : the Journal of the International Menopause Society
L P CheungC J Haines

Abstract

The aim of this study was to investigate acute changes in serum concentrations of lipoprotein(a) and other atherogenic lipids and lipoproteins after a surgical menopause. A total of 100 premenopausal Chinese women who were booked for hysterectomy for benign gynecological disorders were recruited. They study group comprised 40 subjects undergoing hysterectomy as well as bilateral oophorectomy. The control group consisted of 60 subjects undergoing hysterectomy with conservation of the ovaries. Complete data were available from 30 of the 40 subjects in the study group and from 44 of the 60 controls. Serum concentrations of lipoprotein(a) and other atherogenic lipids and lipoproteins were measured before surgery and these measurements were repeated 3 days, 8 weeks and 6 months postoperatively. Those study patients who received hormone replacement therapy and control patients who became menopausal, according to biochemical criteria, during the study period were excluded from analysis. Three days after surgery, there was a significant increase in the mean lipoprotein(a) concentration in the control group from 19.1 to 23.0 mg/dl (p < 0.01), but there was no significant change in the study group. There were no significant changes from ...Continue Reading

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Citations

May 4, 2007·Menopause : the Journal of the North American Menopause Society·Rogerio A Lobo
Oct 31, 2008·Menopause : the Journal of the North American Menopause Society·William H Parker, JoAnn E Manson
Apr 9, 2011·The Journal of Clinical Endocrinology and Metabolism·Xuewen WangBettina Mittendorfer
Aug 26, 2009·Women's Health·William H ParkerWalter Rocca
Jan 30, 2016·Climacteric : the Journal of the International Menopause Society·Y CuiA O Mueck
Jun 15, 2004·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·James F WellehanVivek Kapur

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