Acute effects of caffeine on heart rate variability in habitual caffeine consumers

Clinical Physiology and Functional Imaging
Robert RauhMichael Mueck-Weymann

Abstract

During the last years, heart rate variability (HRV) has become a promising risk factor for cardiovascular events. However, the effect of caffeine on HRV in habitual caffeine consumers has barely been investigated. Therefore, we treated 30 male habitual caffeine users in a randomized double-blinded crossover study design with either placebo, 100 or 200 mg caffeine orally and determined parameters of HRV under resting conditions and metronomic breathing. As result, we could not detect significant differences in HRV parameters up to 90 min after drug ingestion. We conclude that modest amounts of caffeine do not reveal negative nor positive effects on HRV within the first 90 min after drug ingestion in young and healthy habitual caffeine consumers. However, further research is necessary to determine the effects of caffeine on HRV in habitual caffeine users, healthy as well as suffering from diabetes, hypertension and postmyocardial infarction.

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Citations

Mar 30, 2007·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Martin SiepmannMichael Mueck-Weymann
Jun 1, 2012·Journal of Caffeine Research·Catherine F Notarius, John S Floras
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Mar 15, 2016·Frontiers in Physiology·Valéria L G PanissaEmerson Franchini
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Jul 14, 2017·Nutrients·Rackel Aguiar Mendes de OliveiraAntonio Luiz Pinho Ribeiro
Oct 25, 2011·Journal of Korean Medical Science·Gyung-Mee Kim, Jong-Min Woo
Oct 18, 2018·European Journal of Sport Science·Paloma da Silva RolimCarlos Janssen Gomes da Cruz
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Apr 26, 2017·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Daniele WikoffCandace Doepker

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