PMID: 20622309Jul 14, 2010Paper

Acute effects of hemodialysis on pulmonary function in patients with end-stage renal disease

Iranian Journal of Kidney Diseases
Rayhaneh RahgoshaiMehrdad Solouki

Abstract

Despite many beneficial effects, hemodialysis may cause pulmonary dysfunction. On the other hand, patients with end-stage renal disease are potentially prone to lung edema and respiratory dysfunction. This study was conducted to evaluate the alterations of pulmonary function indicators after hemodialysis, measured by spirometry. A total of 26 patients on hemodialysis for at least 3 months were studied. They were all older than 18 years old. None of the patients was a current or recent smoker, and none of them had a history of respiratory diseases, current or recent respiratory infections, musculoskeletal disorders, or tuberculosis. All of the patients underwent the spirometry test before and after a 4-hour hemodialysis session, and the forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), vital capacity (VC), and FEV1/FVC ratio were measured. After hemodialysis, the FVC significantly increased (P = .02), while no significant improvement in the FEV1, VC, and FEV1/FVC ratio were observed. Gender was related to the changes in VC, with better results in women (P < .001). There was no association between the changes in spirometry parameters and age, body mass index, cause of kidney failure, type of anion ...Continue Reading

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