Acute effects of selective fetoscopic laser photocoagulation on recipient cardiac function in twin-twin transfusion syndrome

American Journal of Obstetrics and Gynecology
Mounira HabliT M Crombleholme

Abstract

This study evaluated the acute effects of selective fetoscopic laser photocoagulation (SFLP) on recipient cardiovascular function in a twin-twin transfusion syndrome (TTTS) pregnancy. This was a retrospective chart review of echocardiographic data in TTTS including right (RV) and left (LV) ventricular Doppler myocardial performance index (MPI); LV and RV end diastolic wall thickness; and umbilical artery (UA), vein (UV), and ductus venosus (DV) Dopplers. The primary outcome measures were improved MPI defined as greater than 10% interval decrease in left and/or right MPI. Data were analyzed by Student t test and Fisher's exact test. Sixty-five patients met inclusion criteria. SFLP results in a significant improvement in UV and DV Doppler and an increase in both RV and LV wall thickness. A 10% or greater improvement in recipient LV MPI after SFLP is associated with improved recipient survival as compared with unimproved LV MPI (100% vs 86.1%, P = .05). Improved recipient myocardial performance index after SFLP is associated with improvement in recipient survival.

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Citations

Sep 3, 2010·International Journal of Pediatrics·Tim Van MieghemJan Deprest
Jun 30, 2009·Clinics in Perinatology·Mounira HabliTimothy Crombleholme
Jun 11, 2011·Prenatal Diagnosis·Cornelia MaschkePeter Bartmann
Jan 3, 2013·Journal of Paediatrics and Child Health·Catherine BarreaCorinne Hubinont
Jul 6, 2011·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·N MerikiA W Welsh
Mar 4, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E Gapp-BornR Favre
Mar 19, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S M LobmaierF Crispi
Jul 1, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D TachibanaK Hecher
May 25, 2015·American Journal of Obstetrics and Gynecology·Jay D PruetzDouglas L Vanderbilt
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Oct 6, 2009·American Journal of Obstetrics and Gynecology·Tim Van MieghemJan Deprest
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Mar 12, 2013·American Journal of Obstetrics and Gynecology·Marisa C Taylor-ClarkeHelena M Gardiner
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