Acute esophageal necrosis following kidney transplantation.

Journal of Medicine and Life
Paul Thomas KronerHani Michel Wadei

Abstract

We are reporting a case of spontaneous acute esophageal necrosis "black esophagus" of unclear etiology in a kidney transplant recipient. A patient with end-stage renal disease due to IgA nephropathy received a deceased-donor kidney transplant. The surgical procedure was uneventful, without hemodynamic instability. He was started on alemtuzumab for immunosuppression induction followed by maintenance immunosuppression with intravenous methylprednisolone for 3 days, then oral prednisone, mycophenolate mofetil and tacrolimus (a target level between 8 and 10ng/ml) daily. On postoperative day (POD) 3, the patient started to develop significant gastro-intestinal symptoms: epigastric pain, dysphagia, odynophagia, eructation, pyrosis, nausea, and regurgitation of food contents. He was diagnosed with esophageal necrosis by upper endoscopy on postoperative day 4. We describe a successful treatment with supportive therapy and complete recovery despite receiving immunosuppressive therapy. To our knowledge, this case is one of the few reported cases of esophageal necrosis in kidney transplant recipients and the first case that was not associated with clinical risk factors.

References

May 25, 2005·Transplant International : Official Journal of the European Society for Organ Transplantation·Claudio Ponticelli, Patrizia Passerini
Feb 23, 2007·Transplant Infectious Disease : an Official Journal of the Transplantation Society·R TrappeP Reinke
Jul 6, 2014·The Annals of Thoracic Surgery·Stephanie G WorrellJeffrey A Hagen
Oct 10, 2014·Digestive Diseases and Sciences·Grigoriy E GurvitsAris Tsiakos
Apr 11, 2015·Clinical Kidney Journal·Fernando Caravaca-FontánCarlos Quereda
Oct 17, 2020·ACG Case Reports Journal·Kaitlin Wanta, Ayokunle T Abegunde

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