PMID: 11932005Apr 5, 2002Paper

Acute exposure of Siberian sturgeon (Acipenser baeri, Brandt) yearlings to nitrite: median-lethal concentration (LC(50)) determination, haematological changes and nitrite accumulation in selected tissues

Aquatic Toxicology
M HuertasF Castelló-Orvay

Abstract

Exposure of Siberian sturgeon (Acipenser baeri) yearlings (172.0+/-18 g; mean+/-S.D.) to several NO(2)(-)-N concentrations (0, 25, 130, 180 and 275 mg/l) was studied for 72 h in static tests. At 72 h, the median-lethal concentration of NO(2)(-)-N was 130 mg/l in water with high chloride content (130.5 mg/l). Nitrite exposure produced high levels of methaemoglobin (MetHb) but did not seem to cause mortality, as surviving fish showed higher levels (82.7+/-5.6%) than torpid specimens (60.8+/-4.5%). Levels of MetHb were unrelated to environmental and plasmatic nitrite concentrations, as both torpid and surviving fish exposed to the highest nitrite levels (275 mg/l of NO(2)(-)-N) presented similar concentrations of MetHb to those exposed to 25 mg/l of NO(2)(-)-N, thus indicating the ability of Siberian sturgeon yearlings to regulate plasmatic nitrite levels and maintain them lower than the environmental concentration of the toxicant. Nitrite exposure caused changes in the plasmatic electrolyte balance, which is characterised by extracellular hyperkalemia, high plasmatic chloride levels and low plasmatic sodium concentration. Differences between the nitrite concentration in the liver of torpid (46.3+/-9.0 mg/l) and surviving specimen...Continue Reading

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Citations

Sep 15, 2012·Environmental Science and Pollution Research International·Loredana StabiliRosa Anna Cavallo
May 3, 2003·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Frank B Jensen
Jan 16, 2013·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·S WuertzJ P Schroeder
Aug 9, 2012·Journal of Aquatic Animal Health·Maria S SepúlvedaJon J Amberg
Nov 6, 2017·The Science of the Total Environment·Márcio José Dos Santos SilvaKleber Campos Miranda-Filho

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