Acute fibrinous and organising pneumonia: a case report and review of the literature.

Journal of Medical Case Reports
Argyris TzouvelekisD Bouros

Abstract

Organising pneumonia is a distinct histopathological entity characterized by intra-alveolar buds of granulation tissue, called Masson bodies, which mainly comprise of activated fibroblasts and loose connective tissue. This histopathologic pattern has been described in idiopathic cases, characterizing cryptogenic organising pneumonia as well as in the context of pulmonary infection, drug-induced pneumonitis and following lung transplantation. Although distinct as a clinical and pathological entity, community organising pneumonia may present with atypical clinical and pathological features, such as intra-alveolar fillings of fibrin balls and organising tissue that resembles acute respiratory distress syndrome or diffuse alveolar damage. The latter characteristics constitute a recently described anatomoclinical entity called acute fibrinous and organising pneumonia. Here, we describe a rare case of acute fibrinous and organising pneumonia, in an otherwise healthy 65-year-old Greek woman who complained of dry cough, fever, weight loss and progressive dyspnoea. She had never been a smoker. Her clinical symptoms showed a rapid deterioration in the two weeks before admission, despite a course of oral antibiotics. After excluding infec...Continue Reading

References

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Nov 15, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Seth J KligermanJeffrey R Galvin

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Citations

Apr 26, 2013·American Journal of Respiratory and Critical Care Medicine·Miranda ParaskevaGlen P Westall
Nov 15, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Seth J KligermanJeffrey R Galvin
Apr 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sarah P GeorgiadouDimitrios P Kontoyiannis
Jul 22, 2011·Enfermedades infecciosas y microbiología clínica·Alba RiberaMiguel Santin
Dec 3, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Maria A KokosiAthol U Wells
Sep 11, 2016·The Clinical Respiratory Journal·Kam Yu ChiuYing Ying Gu
Jun 26, 2013·Annals of Saudi Medicine·Thamer H Al-KhouzaieAlbader M Hazmi
Sep 9, 2017·BMJ Case Reports·João Rocha GonçalvesLeila Cardoso

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Methods Mentioned

BETA
bronchoalveolar lavage
lavage
biopsy
biopsies
bronchoalveolar

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