Acute Flaccid Myelitis: A Single Pediatric Center Experience From 2014 to 2019.

Journal of Child Neurology
Rifali PatelSumit Verma

Abstract

Acute flaccid myelitis has emerged as the leading cause of acute flaccid paralysis in children. Acute flaccid myelitis leads to significant physical disability; hence, objective outcome measures to study disease severity and progression are desirable. In addition, nerve transfer to improve motor function in affected children needs further study. Retrospective study of acute flaccid myelitis subjects managed at Children's Healthcare of Atlanta from August 2014 to December 2019. Clinical, electromyography and nerve conduction study, neuropsychological functional independence (WeeFIM), and nerve transfer data were reviewed. Fifteen children (11 boys and 4 girls) mean age 5.1±3.2 years (range 14 months to 12 years) were included. All subjects (n = 15) presented with severe asymmetric motor weakness and absent tendon reflexes. Motor nerve conduction study of the affected limbs in 93% (n = 14) showed absent or markedly reduced amplitude. Ten patients received comprehensive inpatient rehabilitation and neuropsychological evaluation. Admission and discharge WeeFIM scores showed deficits most consistent and pronounced in the domains of self-care and mobility. Multiple nerve transfer surgery was performed on 13 limbs (9 upper and 4 lower...Continue Reading

References

Nov 24, 1999·American Journal of Medical Genetics·M E Msall, M R Tremont
May 17, 2002·The Journal of Hand Surgery·Christine CurtisDavid Andrews
Jun 18, 2015·Muscle & Nerve·Inger Anette Hynås Hovden, Helle Cecilie Viekilde Pfeiffer
Jul 17, 2016·Annals of Neurology·Kevin MessacarSamuel R Dominguez
Jun 16, 2017·Neurology·Jan A MartinTeri L Schreiner
Jun 16, 2017·Neurology·Max Wiznitzer, Avindra Nath
Jun 24, 2017·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·E W AndersenM M Ryan
Oct 12, 2018·Pediatric Neurology·Eliana B SaltzmanScott W Wolfe
Dec 31, 2018·Brain & Development·Akihisa OkumuraUNKNOWN Acute Flaccid Myelitis Collaborative Study Investigators
Oct 9, 2019·Pediatrics·Tracy AyersManisha Patel

❮ Previous
Next ❯

Citations

Feb 24, 2021·Plastic and Reconstructive Surgery·Kevin J Zuo, Kristen M Davidge

❮ Previous
Next ❯

Software Mentioned

Synergy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatrics in Review
Daniel R Taylor, Sharyu Krishnakumar
CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
Peter J GillE Ann Yeh
JAMA : the Journal of the American Medical Association
Bridget Kuehn
Nursing
Alyssa Francis, Bridget Parsh
The Lancet Child & Adolescent Health
Aaron Van Dorn
© 2021 Meta ULC. All rights reserved