Acute fulminant pseudomembranous colitis which developed after ileostomy closure and required emergent total colectomy: a case report.

Journal of Medical Case Reports
Iku AbeFumio Konishi

Abstract

Pseudomembranous colitis is known to be caused by Clostridium difficile; and, in 3% to 8% of patients, it lapses into an aggressive clinical course that is described as fulminant. We present here a case of extremely rapid and fatal fulminant pseudomembranous colitis that developed after ileostomy closure, a minor surgical procedure. To the best of our knowledge, this is the first case report of fatal fulminant pseudomembranous colitis after closure of a diversion ileostomy in an adult. A 69-year-old Japanese man, who had previously undergone low anterior resection and creation of a diverting ileostomy for stage III rectal carcinoma was admitted for ileostomy closure. Preoperatively, he received oral kanamycin and metronidazole along with parenteral cefmetazole. His surgery and postoperative course were uneventful until the third postoperative day, when fever and watery diarrhea became apparent. The next day he presented with epigastric and left lower abdominal pain. Computed tomography revealed a slightly distended colon. Later that night, his blood pressure fell and intravenous infusion was started. In the early morning of the fifth postoperative day, his blood pressure could be maintained only with a vasopressor. Follow-up co...Continue Reading

References

Sep 1, 1995·Archives of Surgery·D KreiselJ D Cunningham
May 1, 1995·American Journal of Surgery·B A JobeB C Sheppard
Mar 21, 1998·The British Journal of Surgery·K SynnottR Quill
Jan 4, 2008·Surgical Infections·Marc ZereyB Todd Heniford
Oct 16, 2008·The American Journal of Gastroenterology·M Raffat JaberMark E Reeves
Apr 1, 2009·Diseases of the Colon and Rectum·Jacques PepinAnnie-Claude Labbé
Apr 23, 2010·American Journal of Surgery·Parag Butala, Celia M Divino

❮ Previous
Next ❯

Citations

May 23, 2016·Cirugia y cirujanos·Luis Tallón-AguilarFrancisco Javier Padillo-Ruiz
Sep 6, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R L HarriesG L Williams
Sep 23, 2015·International Cancer Conference Journal·Yuki SakamotoHideo Baba
Mar 18, 2020·Annals of Coloproctology·Ho Seung KimNam Kyu Kim
Aug 6, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Simon J G RichardsIan P Hayes

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.