Acute generalized exanthematous pustulosis-like, folliculitic drug reaction pattern caused by celecoxib

Dermatologic Therapy
Janthorn PakdeethaiKong Bing Tan

Abstract

An extensive range of diseases or reactions can cause pustular eruptions of the skin. Drug-provoked cutaneous eruptions includes acute generalized exanthematous pustulosis (AGEP) and acneiform eruption. We report a 50-year-old man who developed fever and a sudden eruption of widespread pustules 12 days after ingestion of celecoxib prescribed for a prolapsed intervertebral disc. AGEP was diagnosed based on the typical history, characteristic features, and laboratory findings. However, histopathological findings were consistent with folliculitic drug reaction pattern without features of AGEP. We present, the first known reported case of folliculitic drug reaction pattern caused by celecoxib.

References

Aug 1, 1991·The Journal of Dermatology·T Kanzaki
Oct 1, 1985·Journal of the American Academy of Dermatology·J P Tindall
Mar 1, 1974·Archives of Dermatology·L K CohenR Smith
Feb 22, 2000·Dermatology : International Journal for Clinical and Investigative Dermatology·M A Fung, T G Berger
Feb 13, 2001·Journal of Cutaneous Pathology·A SidoroffJ C Roujeau
Oct 27, 2004·Expert Opinion on Drug Safety·Noah Scheinfeld
Sep 19, 2007·Archives of Dermatology·Lucio Bakos, Renato Marchiori Bakos
Aug 23, 2008·American Journal of Clinical Dermatology·Madeleine Duvic

❮ Previous
Next ❯

Citations

May 4, 2013·Immunology and Allergy Clinics of North America·Katharine M Woessner, Mariana Castells
Mar 15, 2016·International Journal of Dermatology·Sofiene LarifChaker Ben Salem

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.