Acute hepatitis C in a patient receiving etanercept

Actas dermo-sifiliográficas
M Armengot-CarbóE Gimeno

Abstract

According to the literature, the use of tumor necrosis factor (TNF) inhibitors in patients with chronic hepatitis C infection is safe and effective. There have been no reports, however, of primary infection with the hepatitis C virus during treatment with a biologic agent. We report the case of a patient with long-standing moderate to severe psoriasis who developed acute hepatitis C while being treated with etanercept. Biologic therapy was continued and the infection was successfully treated with pegylated interferon, which achieved a sustained virologic response. Etanercept did not have a negative impact on disease outcome or on response to antiviral treatment.

References

May 15, 2010·Journal of the American Academy of Dermatology·Andrea ParadisiClara De Simone
Mar 5, 2011·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver

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Citations

Aug 30, 2013·Expert Opinion on Drug Safety·Hong Yang, Arthur Kavanaugh
May 13, 2020·Expert Review of Clinical Pharmacology·Ya-Chu Tsai, Tsen-Fang Tsai

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