PMID: 11606863Oct 19, 2001Paper

Acute hepatitis E virus infection presenting as a prolonged cholestatic jaundice

Journal of Clinical Gastroenterology
L MechnikS Malnick

Abstract

Hepatitis E virus (HEV) is an enteric virus that usually causes a self-resolving hepatitis; although, it may be fatal, especially in pregnant women. Although HEV is endemic in Israel, there have been no recent local outbreaks. We report the case of a 70-year-old man who presented with painless jaundice. Ultrasound and abdominal computed tomography scan revealed gallstones, with no evidence of cholecystitis and no dilatation of the intra-or extrahepatic bile ducts. An open cholecystectomy was performed with intraoperative cholangiography. There was no evidence of choledocholithiasis. A subsequent endoscopic retrograde cholangiopancreatography was normal. His bilirubin level subsequently increased to a maximum of 25 mg/dL, and his gamma-glutamyl-transferase level reached 1,400 U/L. There was no evidence of any autoimmune or metabolic disease, and routine viral serology was normal except for immunoglobulin G to hepatitis A virus. A liver biopsy revealed an acute cholestatic picture. The jaundice resolved slowly after a period of 6 months. Hepatitis E virus RNA was isolated from the acute-phase serum and was not detectable in the convalescent serum. This case is a unique example of chronic cholestatic jaundice that we think is caus...Continue Reading

References

Mar 1, 1995·Journal of Medical Virology·Y V KaretnyiE Levin
Feb 1, 1995·JAMA : the Journal of the American Medical Association·S P SylvanH Troonen
Jan 16, 1993·Lancet·A ChauhanN K Ganguly
Jan 1, 1996·Annual Review of Medicine·E E Mast, K Krawczynski
Jun 1, 1997·Journal of Clinical Gastroenterology·W C ChowH S Ng

❮ Previous
Next ❯

Citations

Feb 22, 2008·The New England Journal of Medicine·Nassim KamarLionel Rostaing
Oct 13, 2006·Current Opinion in Gastroenterology·Michael Trauner, James L Boyer
Aug 7, 2004·Journal of Clinical Microbiology·Yuko KoizumiHiroaki Okamoto
Jan 18, 2013·World Journal of Gastroenterology : WJG·Bin XuXin-Hui Guo
Jan 26, 2010·Néphrologie & thérapeutique·Nassim KamarLionel Rostaing
Jan 5, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Hélène Blasco-PerrinJean Marie Péron
Mar 30, 2011·Virus Research·Tatsuo Miyamura
Mar 17, 2007·Virus Research·Hiroaki Okamoto
Apr 19, 2007·Journal of Viral Hepatitis·H R DaltonD F Levine
Jun 19, 2008·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·N KamarL Rostaing
Jan 1, 2009·Medical Journal, Armed Forces India·B NandiR K Ganjoo
Dec 22, 2007·Journal of Medical Virology·Aminda N De SilvaEmanuela Pelosi
Dec 1, 2007·European Journal of Gastroenterology & Hepatology·Rami MoucariTarik Asselah
Jul 1, 2014·Current Opinion in Infectious Diseases·Yijin WangQiuwei Pan
May 8, 2018·Cold Spring Harbor Perspectives in Medicine·Rakesh Aggarwal, Amit Goel
Jun 29, 2016·World Journal of Gastroenterology : WJG·Ortal Erez-GranatEli Schwartz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved