Acute hyperhydration reduces athlete biological passport OFF-hr score

Scandinavian Journal of Medicine & Science in Sports
Jacob BejderJ Mørkeberg

Abstract

Anecdotal evidence suggests that athletes hyperhydrate to mask prohibited substances in urine and potentially counteract suspicious fluctuations in blood parameters in the athlete biological passport (ABP). It is examined if acute hyperhydration changes parameters included in the ABP. Twenty subjects received recombinant human erythropoietin (rhEPO) for 3 weeks. After 10 days of rhEPO washout, 10 subjects ingested normal amount of water (∼ 270 mL), whereas the remaining 10 ingested a 1000 mL bolus of water. Blood variables were measured 20, 40, 60, and 80 min after ingestion. Three days later, the subjects were crossed-over with regard to water ingestion and the procedure was repeated. OFF-hr was reduced by ∼ 4%, ∼ 3%, and ∼ 2% at 40, 60, and 80 min, respectively, after drinking 1000 mL of water, compared with normal water ingestion (P < 0.05). Forty percent of the subjects were identified with atypical blood profiles (99% specificity level) before drinking 1000 mL of water, whereas 11% (n = 18), 10% and 11% (n = 18) were identified 40, 60, and 80 min, respectively, after ingestion. This was different (P < 0.05) compared with normal water intake, where 45% of the subjects were identified before ingestion, and 54% (n = 19), 45%,...Continue Reading

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Citations

Oct 4, 2016·Drug Testing and Analysis·Jacob BejderNikolai Baastrup Nordsborg
Apr 29, 2015·Scandinavian Journal of Medicine & Science in Sports·D ReljicB Friedmann-Bette
Nov 26, 2016·Drug Testing and Analysis·Mario ThevisWilhelm Schänzer
Feb 1, 2017·Scandinavian Journal of Medicine & Science in Sports·J BejderN B Nordsborg
Mar 28, 2020·Drug Testing and Analysis·Jacob BejderCarsten Lundby
Jun 22, 2018·Frontiers in Physiology·Michael J PuchowiczDavid C Clarke
Aug 18, 2020·Journal of Sports Medicine·Johan O Wedin, Anders E Henriksson
Jun 19, 2018·European Journal of Sport Science·L M LobigsY O Schumacher
Jul 23, 2020·Medicine and Science in Sports and Exercise·Jacob BejderNikolai Baastrup Nordsborg
Dec 17, 2020·American Journal of Hematology·Veronika MussackMichael W Pfaffl
Oct 24, 2020·The Journal of Sports Medicine and Physical Fitness·Roman AlbertyMiloš BÁtovskÝ
May 17, 2021·Clinical Chemistry·Holly D CoxDaniel Eichner
Sep 16, 2021·Sports Medicine - Open·Bastien Krumm, Raphael Faiss

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