PMID: 4051545Sep 1, 1985Paper

Acute hypothyroidism in a 3 year old

Archives of Disease in Childhood
U MacFadyenP G Swift


A 3 year old girl presented with a three week history of lethargy, constipation, and joint swelling. Investigation showed primary hypothyroidism associated with immunological changes including thyroglobulin antibodies. Reassessment several months after beginning thyroxine treatment confirmed persisting hypothyroidism. Primary hypothyroidism may present as a rapid onset disorder.


Nov 1, 1966·The Journal of Pediatrics·J WinterA M Bongiovanni
Sep 25, 1980·The New England Journal of Medicine·N MatsuuraK Wataya
Jan 1, 1959·The Journal of Clinical Endocrinology and Metabolism·L B WOOLNERO H BEAHRS

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Oct 1, 1988·Journal of Medical Genetics·J P Fryns, K Chrzanowska

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