PMID: 16502732Mar 1, 2006Paper

Acute immune thrombocytopenic purpura in children and adolescents in South Dakota 1998-2004

South Dakota Journal of Medicine
Jakica TancabelicJulie Wetering

Abstract

Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura, is a rare bleeding disorder caused by increased peripheral platelet destruction. The laboratory and clinical criteria for establishing the diagnosis of acute ITP in children and adolescents are widely accepted. Treatment options for ITP remain controversial. Retrospective data analysis of patients with acute ITP referred to the pediatric Hematology/Oncology Clinic at Sioux Valley Children's Specialty Clinic, seen from August 1998 to December 2004. Fourteen patients out of 25 presented with acute ITP, and had platelet count < or = 10 x 10(9)/L. Life threatening hemorrhage did not occur with any of these patients. Eleven of the analyzed 25 (44%) patients had thrombocytopenia resolve within six months of diagnosis. Nine patients (9/25, 36%) continue to be thrombocytopenic at one year from diagnosis, but without significant bleeding episodes. The clinical presentation, duration and severity of disease in patients with acute ITP seen in our Center are similar to those described in recently published studies. Our approach to treatment differed when compared with other studies. The difference in treatment may be due to patients' significant geogr...Continue Reading

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.