Acute kidney injury after pediatric cardiac surgery: risk factors and outcomes. Proposal for a predictive model

Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
Bárbara CardosoFátima Pinto

Abstract

To characterize the epidemiology and risk factors for acute kidney injury (AKI) after pediatric cardiac surgery in our center, to determine its association with poor short-term outcomes, and to develop a logistic regression model that will predict the risk of AKI for the study population. This single-center, retrospective study included consecutive pediatric patients with congenital heart disease who underwent cardiac surgery between January 2010 and December 2012. Exclusion criteria were a history of renal disease, dialysis or renal transplantation. Of the 325 patients included, median age three years (1 day-18 years), AKI occurred in 40 (12.3%) on the first postoperative day. Overall mortality was 13 (4%), nine of whom were in the AKI group. AKI was significantly associated with length of intensive care unit stay, length of mechanical ventilation and in-hospital death (p<0.01). Patients' age and postoperative serum creatinine, blood urea nitrogen and lactate levels were included in the logistic regression model as predictor variables. The model accurately predicted AKI in this population, with a maximum combined sensitivity of 82.1% and specificity of 75.4%. AKI is common and is associated with poor short-term outcomes in thi...Continue Reading

References

Mar 1, 1985·The Journal of Pediatrics·G J Schwartz, B Gauthier
Mar 31, 2007·Kidney International·A Akcan-ArikanS L Goldstein
Dec 31, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Cherry MammenDouglas G Matsell

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Citations

Sep 23, 2018·Clinical Journal of the American Society of Nephrology : CJASN·Omar AlkandariLisa A Robinson
Jun 6, 2019·Revista da Associação Médica Brasileira·Mauro FisbergGerson Luis de Moraes Ferrari
Dec 6, 2018·Revista brasileira de epidemiologia = Brazilian journal of epidemiology·Deborah Carvalho MaltaKarla Santa Cruz Coelho
Jan 9, 2018·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Shahram AminiMohammad Abbasi Tashnizi

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