Acute Kidney Injury After Percutaneous Edge-to-Edge Mitral Repair.

Journal of the American College of Cardiology
Germán ArmijoLuis Nombela-Franco

Abstract

In catheter-based procedures, acute kidney injury (AKI) is a frequent, serious complication ranging from 10% to 30%. In MitraClip (Abbott Vascular, Santa Clara, California), a usually contrast-free procedure, there is scarce data about its real incidence and impact. This study aimed to evaluate incidence, predictive factors, and midterm outcomes of AKI in patients with significant mitral regurgitation (MR) undergoing transcatheter valve repair with MitraClip. A total of 721 patients undergoing MitraClip were included. AKI was defined as an absolute or a relative increase in serum creatinine of >0.3 mg/dl or ≥50%, respectively, or the need for hemodialysis during index hospitalization. The mean age of the patients was 72 ± 11 years (28.3% women). Median estimated glomerular filtration rate (eGFR) was 43.7 ml/min/1.73 m2 (interquartile range: 30.9 to 60.1 ml/min/1.73 m2), and was <60 ml/min/1.73 m2 in 74.9% of the patients. AKI after MitraClip occurred in 106 patients (14.7%). Baseline hemoglobin (<11 g/dl) (odds ratio [OR]: 1.97; p = 0.003), urgent procedure (OR: 3.44; p = 0.003), and absence of device success (OR: 3.37; p < 0.001) were independent predictors of AKI. Patients with AKI had worse outcomes compared to those without...Continue Reading

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Citations

Apr 16, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Eduardo Martinez-GomezLuis Nombela-Franco
Apr 16, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Salik NazirHani Jneid
Jun 22, 2021·International Journal of Cardiology·Manuel Pan, Soledad Ojeda
Aug 3, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Ilias P DoulamisGilbert H L Tang
Nov 21, 2020·Journal of the American College of Cardiology·George D Dangas, David H Adams

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