Acute Kidney Injury and Kidney Damage in COVID-19 Patients

Journal of Korean Medical Science
Ki Ryang NaJae Wan Jeon

Abstract

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This disease, which is quickly spreading worldwide, has high potential for infection and causes rapid progression of lung lesions, resulting in a high mortality rate. This study aimed to investigate the effects of SARS-CoV-2 infection on renal function in patients with COVID-19. From February 21 to April 24, 2020, 66 patients diagnosed with COVID-19 at Chungnam National University Hospital were analyzed; all patients underwent routine urinalysis and were tested for serum creatinine, urine protein to creatinine ratio (PCR), and urine albumin to creatinine ratio (ACR). Acute kidney injury (AKI) occurred in 3 (4.5%) of the 66 patients, and 1 patient with AKI stage 3 underwent hemodialysis. Upon follow-up, all 3 patients recovered normal renal function. Compared with patients with mild COVID-19, AKI (n = 3) occurred in patients with severe COVID-19, of whom both urine PCR and ACR were markedly increased. The incidence of AKI was not high in COVID-19 patients. The lower mortality rate in SARS-CoV-2 infection compared with previous Middle East respiratory syndrome and SARS-CoV infections is thought to be associated...Continue Reading

References

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Citations

Feb 23, 2021·Reviews in Endocrine & Metabolic Disorders·Giovanni CoronaMario Maggi
Aug 2, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Zeynab Mohamadi Yarijani, Houshang Najafi
Sep 14, 2021·Journal of Zhejiang University. Science. B·Zhifeng ZhouLing Zhang
May 25, 2021·Journal of Research in Health Sciences·Naser NasiriAli Sharifi

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Methods Mentioned

BETA
PCR

Software Mentioned

SPSS

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