Abstract
Acute kidney injury (AKI) is the most common and most serious complication following heart surgery. We aimed to determine the prevalence of, and risk factors for, AKI following pediatric cardiac surgery.Methods and Results:We retrospectively analyzed 135 patients aged ≤18 years who underwent cardiac surgery for congenital heart defects; by RACHS-1 category, 58 patients (43%) had an operative risk score ≥3. AKI was defined and classified using the pediatric pRIFLE criteria (Pediatric Risk, Injury, Failure, Loss, and End-stage Kidney Disease); 19 patients (14.1%) developed AKI: 17 had AKI with a severity classified as risk (R) and 2 had AKI classified as injury (I). Body weight, height, body surface area, and preoperative mechanical ventilation were all independently associated with AKI development (P=0.038, 0.040, 0.033 and 0.008, respectively). Preoperative ventilation strongly correlated with AKI severity. Higher pRIFLE classification positively correlated with increased incidence of peritoneal dialysis, increased postoperative mechanical ventilation duration, and longer hospital stay (P=0.009, 0.039 and 0.042, respectively). In this study, we found a low prevalence of postoperative AKI in pediatric patients undergoing severe ...Continue Reading
References
Jun 1, 1984·The Journal of Pediatrics·G J SchwartzD J Langford
Jul 17, 2001·Pediatric Cardiology·J E Kist-van Holthe tot EchtenM G Hazekamp
Sep 14, 2002·Clinical Nephrology·Y FujimotoM Nagashima
Mar 31, 2007·Kidney International·A Akcan-ArikanS L Goldstein
Jul 31, 2009·Kidney International·Michael ZappitelliOmar Alkandari
Dec 23, 2009·Pediatrics and Neonatology·Jen-Chung ChienPi-Chang Lee
Feb 22, 2011·Critical Care Medicine·Simon LiUNKNOWN TRIBE-AKI Consortium
Mar 3, 2011·Nature Reviews. Nephrology·Zaccaria RicciClaudio Ronco
Apr 12, 2011·Clinical and Experimental Nephrology·Sidharth Kumar SethiAtul Juneja
Jul 30, 2011·The Journal of Thoracic and Cardiovascular Surgery·Joshua J BlinderJohn L Jefferies
Nov 19, 2011·Journal of the American College of Cardiology·Catherine D KrawczeskiPrasad Devarajan
Jan 10, 2012·The Annals of Thoracic Surgery·Roland TóthAndrea Székely
Apr 25, 2012·Intensive Care Medicine·Jesse DavidsonJon Kaufman
Aug 14, 2012·The Annals of Thoracic Surgery·Scott I AydinJames Schneider
Aug 21, 2012·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·Kirsten Pedersen
Oct 9, 2012·The Journal of Thoracic and Cardiovascular Surgery·Marnie L TaylorSatish K Rajagopal
Feb 23, 2013·Pediatric Cardiology·Zaccaria RicciPaola Cogo
Mar 23, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Abdullah AlabbasCherry Mammen
Aug 29, 2014·Cardiology in the Young·Efrén Martínez-Quintana, Fayna Rodríguez-González
Citations
Dec 7, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Fu-Shan XueGui-Zhen Yang
Dec 7, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Seon Hwa Lee, Soo-Jin Kim
Sep 5, 2017·Nature Reviews. Nephrology·Ying Wang, Rinaldo Bellomo
Mar 30, 2019·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Denise C HassonKatja M Gist
May 20, 2020·Cardiology in the Young·Sara Rodriguez-LopezCatherine Morgan
Dec 25, 2019·Pediatric Cardiology·Fumiya YoneyamaSatoshi Yasukouchi
Sep 5, 2019·Perfusion·Hong LiuJin-Rong Xue
Jul 29, 2020·Asian Cardiovascular & Thoracic Annals·Michael CaesarioBudi Rahmat
Aug 11, 2020·Kidney Research and Clinical Practice·Aditya SharmaRupesh Raina
Feb 8, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Shengwen GuoJinping Liu
Jul 27, 2021·Frontiers in Pediatrics·Yuan JiaFuxia Yan
Aug 6, 2021·Frontiers in Pediatrics·Fan CaoMinghui Zou
Oct 9, 2021·Clinical Journal of the American Society of Nephrology : CJASN·Jef Van den EyndeDjalila Mekahli
Oct 9, 2021·Journal of the American Heart Association·Steven L RathgeberKevin C Harris
Nov 5, 2021·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Ying Kiat TanTheo Kofidis