Acute Kidney Injury Incidence in Noncritically Ill Hospitalized Children, Adolescents, and Young Adults: A Retrospective Observational Study

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Tracy L McGregorSara L Van Driest

Abstract

Acute kidney injury (AKI) has been characterized in high-risk pediatric hospital inpatients, in whom AKI is frequent and associated with increased mortality, morbidity, and length of stay. The incidence of AKI among patients not requiring intensive care is unknown. Retrospective cohort study. 13,914 noncritical admissions during 2011 and 2012 at our tertiary referral pediatric hospital were evaluated. Patients younger than 28 days or older than 21 years of age or with chronic kidney disease (CKD) were excluded. Admissions with 2 or more serum creatinine measurements were evaluated. Demographic features, laboratory measurements, medication exposures, and length of stay. AKI defined as increased serum creatinine level in accordance with KDIGO (Kidney Disease: Improving Global Outcomes) criteria. Based on time of admission, time interval requirements were met in 97% of cases, but KDIGO time window criteria were not strictly enforced to allow implementation using clinically obtained data. 2 or more creatinine measurements (one baseline before or during admission and a second during admission) in 2,374 of 13,914 (17%) patients allowed for AKI evaluation. A serum creatinine difference ≥0.3mg/dL or ≥1.5 times baseline was seen in 722 ...Continue Reading

References

Sep 24, 2005·Journal of the American Society of Nephrology : JASN·Glenn M ChertowDavid W Bates
Dec 24, 2005·Kidney International·D J AskenaziS L Goldstein
Mar 3, 2007·Critical Care : the Official Journal of the Critical Care Forum·Ravindra L MehtaUNKNOWN Acute Kidney Injury Network
Mar 31, 2007·Kidney International·A Akcan-ArikanS L Goldstein
Apr 18, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Michael ZappitelliStuart L Goldstein
Jun 4, 2008·Intensive Care Medicine·Frans B PlötzArend Bökenkamp
Jul 2, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael ZappitelliStuart L Goldstein
Jan 8, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Brady S Moffett, Stuart L Goldstein
Feb 15, 2011·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Brady S MoffettAntonio R Mott
Mar 3, 2011·Nature Reviews. Nephrology·Zaccaria RicciClaudio Ronco
Dec 31, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Cherry MammenDouglas G Matsell
Feb 27, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Rajit K BasuStuart L Goldstein
Apr 11, 2014·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Kevin J DownesStuart L Goldstein

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Citations

Jun 17, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Norbert LameireRaymond Vanholder
Dec 23, 2016·Journal of the American Society of Nephrology : JASN·Jessica Sheehan TangrenRavi Thadhani
Jun 3, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Palen P Mallory, Geoffrey M Fleming
Apr 10, 2018·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Erika O BernardoAyse Akcan Arikan
Jan 28, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Vaka K SigurjonsdottirScott M Sutherland
Jun 20, 2018·Hypertension·Jessica Sheehan TangrenRavi Thadhani
Oct 4, 2018·PloS One·Brady S MoffettAyse Akcan-Arikan
Oct 6, 2018·Clinical Journal of the American Society of Nephrology : CJASN·Xin XuFan Fan Hou
Jul 29, 2018·Journal of the American Society of Nephrology : JASN·Xin XuFan Fan Hou
Aug 23, 2019·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Jean-Philippe Roy, Catherine S Forster
Oct 31, 2019·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Elizabeth GoswamiJason Misurac
Aug 28, 2019·Pediatric Research·Sara L Van DriestGordon Bernard
Jan 16, 2020·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Justin B SearnsDanielle E Soranno
Sep 28, 2018·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Rhys D R EvansUlla Hemmila
Feb 15, 2020·International Journal of Molecular Sciences·Claudia Muhle-GollJens H Westhoff
Feb 2, 2018·Current Opinion in Pediatrics·David T SelewskiJennifer R Charlton
Jan 25, 2019·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Ahmad KaddourahUNKNOWN Assessment of Worldwide Acute Kidney Injury, Renal Angina and, Epidemiology (AWARE) Investigators
Jul 1, 2020·Clinical Chemistry and Laboratory Medicine : CCLM·Stan J F HartmanSaskia N de Wildt
Jun 10, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Sainath RamanLuregn J Schlapbach
Oct 28, 2019·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Amanda M Uber, Scott M Sutherland
Sep 8, 2018·World Journal of Clinical Pediatrics·Toru Watanabe
Jan 31, 2020·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Erica C BjornstadEmily W Gower
May 15, 2020·Archives of Disease in Childhood·Blake J SanderySean E Kennedy
Mar 29, 2018·Journal of the Pediatric Infectious Diseases Society·Kathryn M CookSara L Van Driest
Nov 13, 2019·Indian Journal of Pediatrics·Jean-Philippe Roy, Prasad Devarajan
Mar 8, 2020·Pediatrics International : Official Journal of the Japan Pediatric Society·Nuntawan PiyaphaneeAchra Sumboonnanonda
Nov 28, 2019·Hospital Pediatrics·Christina BradshawShuchi Anand
May 7, 2020·Current Opinion in Pediatrics·Asaf LebelMichael Zappitelli
Jun 25, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Emily L JoyceJohn A Kellum
Dec 7, 2019·Clinical Kidney Journal·Alasdair HendersonDorothea Nitsch
Jul 12, 2020·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Dunya MohammadRossana Baracco
Jun 12, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Stefanie Woolridge Benoit, Prasad Devarajan
Jan 13, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·David T SelewskiTheresa Ann Mottes
Feb 2, 2021·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Peter NourseMignon McCulloch

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