Acute kidney injury without previous renal disease in critical care unit.

Pediatrics International : Official Journal of the Japan Pediatric Society
Nuntawan PiyaphaneeAchra Sumboonnanonda

Abstract

Acute kidney injury (AKI) is common in hospitalized and critically ill children. Apart from primary kidney disease, etiologies of AKI are usually related to systemic disease and nephrotoxic insult. This study examines the incidence, characteristics, and mortality risks of AKI in critically ill children without primary renal disease or previously known chronic kidney disease. A retrospective cohort study was conducted of patients aged 1-18 years, diagnosed with AKI (excluding severe glomerulonephritis and previously known chronic kidney disease) in pediatric intensive care units between 2013 and 2016. Acute kidney injury was defined according to the Kidney Disease Improving Global Outcomes classifications. Cox proportional hazards regression analysis was employed to assess the relationship between the risk factors and mortality. Of 1,377 pediatric intensive care unit patients, 253 (18.4%) developed AKI and only 169 (12.3%) who did not have previously known renal disease were included. Of these 169 AKI patients, the mean age was 8.1 ± 4.7 years; 88 (52.1%) patients were male; and 60 (35.5%) patients had AKI stage 3. The most common etiologies of AKI were sepsis (76.9%) and shock (64.5%). Fifty-three (31.4%) of those patients died...Continue Reading

References

Jan 8, 2005·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Brahm GoldsteinUNKNOWN International Consensus Conference on Pediatric Sepsis
Feb 8, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Shirley Hui-StickleStuart L Goldstein
Dec 12, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Deepak DewanAlok Kumar
Apr 4, 2008·Kidney International·C Y HsuA S Go
Jul 2, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael ZappitelliStuart L Goldstein
Apr 19, 2011·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Neesh PannuUNKNOWN Alberta Kidney Disease Network
Nov 28, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Nilzete BresolinClarissa Alberton Haas
Oct 18, 2013·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sriram KrishnamurthySadagopan Srinivasan
Jul 6, 2014·The New England Journal of Medicine·Lakhmir S ChawlaPaul L Kimmel
Feb 5, 2015·Clinical Journal of the American Society of Nephrology : CJASN·Scott M SutherlandStuart L Goldstein
Jul 2, 2015·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·L Nelson Sanchez-PintoRobinder G Khemani
Sep 1, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Tracy L McGregorSara L Van Driest
Aug 12, 2016·Critical Care Medicine·Julie C FitzgeraldUNKNOWN Sepsis PRevalence, OUtcomes, and Therapies Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators Netw
Aug 21, 2016·Pediatrics International : Official Journal of the Japan Pediatric Society·Nuntawan PiyaphaneeAchra Sumboonnanonda
Dec 14, 2016·The New England Journal of Medicine·Ahmad KaddourahUNKNOWN AWARE Investigators
Sep 17, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Jameela A KariAmr S Albanna
Jun 28, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Julie C FitzgeraldAmanda Hyre Anderson
Feb 28, 2019·Journal of Pharmacy Practice·William B Hays, Emma Tillman

❮ Previous
Next ❯

Citations

May 16, 2020·Mediators of Inflammation·Xiaomeng TangChunxia Wang

❮ Previous
Next ❯

Related Concepts

Related Feeds

© 2021 Meta ULC. All rights reserved