Acute large bowel pseudo-obstruction due to multiple myeloma

Leukemia & Lymphoma
Ioannis VenizelosVasiliki Garipidou

Abstract

Involvement of the gastrointestinal (GI) tract by multiple myeloma (MM) is extremely rare. The small intestine and stomach are the most frequent sites of spread. We report 1 case of a 61-year-old woman who presented with clinical and radiographic features of an acute large bowel pseudo-obstruction. An abdominal computerized tomography (CT) showed a large tumor of the rectum. On morphological and immunohistochemical examination the tumor fulfilled the criteria of MM. The patient received combined chemotherapy and radiotherapy which led to the disappearance of the tumor. A review of the literature revealed that this is the first reported case of MM presented as acute large bowel pseudo-obstruction due to a rectal myeloma tumor.

References

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Jan 19, 2000·The American Journal of Gastroenterology·R N KoppelmanA I Rogers
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Mar 26, 2003·Histopathology·G AmonkarS Shinde

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Citations

Jun 10, 2008·Digestive Diseases and Sciences·Osman ErsoyYusuf Bayraktar
Jul 15, 2006·Leukemia & Lymphoma·Zaher K OtrockAli I Shamseddine
Nov 5, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anne HerbstRobert S Krouse

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