Acute leukemia following combination chemotherapy for cancer of the lung

Oncology
J T MayJ J Costanzi

Abstract

A 64-year-old male with recurrent metastatic squamous cell carcinoma was successfully treated with intensive combination chemotherapy. His complete remission was maintained with a nitrosourea, nitrogen mustard and methotrexate for 3 years. While in remission the patient developed acute leukemia. It appears that this secondary malignancy was due to his prolonged chemotherapy.

Citations

Mar 1, 1984·Cancer Treatment Reviews·K Rieche
Nov 3, 1983·The New England Journal of Medicine·J D BoiceJ F Fraumeni
Sep 1, 1982·Cancer Treatment Reviews·D SchmählI Wagner

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