Acute Limb Ischemia in Pediatric Population Secondary to Peripheral Vascular Cannulation: Literature Review and Recommendations

Vascular and Endovascular Surgery
Umar SadatKevin Varty

Abstract

In this article, we discuss published literature on the management of pediatric patients with acute limb ischemia and also present our center's experience. Literature review suggests that in the absence of imminent risk of limb loss, noninterventional management with anticoagulants and systemic thrombolysis is preferable and associated with better clinical outcomes than surgery such as reduced per operative morbidity and mortality. In selected more severe cases, surgery may be required. We propose an algorithm for improved clinical outcomes based on the published literature and the American College of Chest Physicians' recommendations for antithrombotic management in the pediatric population. Literature review suggests an inverse relationship between age and surgical success, particularly in preschool pediatric population. Conservative management as a preliminary strategy seems most beneficial. It is hoped that the proposed intercalated algorithm of medical and surgical management of these patients can further improve clinical outcomes.

References

Jan 1, 1970·The Journal of Pediatrics·H J WiggerW A Blanc
Feb 1, 1982·AJR. American Journal of Roentgenology·E A FrankenJ A Smith
Dec 1, 1982·Journal of Pediatric Surgery·M D KleinE A Lebowitz
May 1, 1981·Archives of Surgery·J D RichardsonL M Flint
Jan 1, 1997·American Journal of Respiratory and Critical Care Medicine·P C YodiceE C Rackow
May 12, 2000·American Journal of Respiratory and Critical Care Medicine·L A KirschenbaumE C Rackow
Jun 13, 2003·Intensive Care Medicine·M PiagnerelliJ-L Vincent
Jan 18, 2006·Journal of Vascular Surgery·Miltos K LazaridesChrysostomos Maltezos
Apr 28, 2006·Plastic and Reconstructive Surgery·Christopher J CoombsPaul Monagle
Oct 18, 2008·Journal of Pediatric Surgery·Niyi Ade-AjayiDavid P Drake
Sep 11, 2012·Pediatric Cardiology·Walter KnirschUNKNOWN Working Group Interventional Cardiology of the German Association of Pediatric Cardiology
Nov 13, 2012·Plastic and Reconstructive Surgery·Cara DowneyJeffrey D Friedman

❮ Previous
Next ❯

Citations

Dec 11, 2019·Journal of Neurointerventional Surgery·Robert M StarkeUNKNOWN Society of NeuroInterventional Surgery
Jan 4, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Martin BjörckKumud Rai
Mar 31, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Tao TangXiaoqiang Li
Apr 21, 2021·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·Cristina Juberías AlzuetaAna Concheiro-Guisán
Aug 18, 2021·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Rafat MosalliBosco Paes

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
amputations

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.