Acute liver disease and encephalopathy mimicking Reye syndrome. A report of three cases.

The Journal of Pediatrics
D G GallM L Greenberg

Abstract

Three patients are described whose clinical presentation suggested Reye syndrome, and in whom the initial laboratory investigations supported the diagnosis. The subsequent clinical and biochemical evolution of the illness differed from that of Reye syndrome. The liver biopsy of each patient revealed changes in centrilobular hepatocytes rather than the diffuse small droplet fatty change characteristic of Reye syndrome. In each of them normal liver functions were regained. The findings in these patients suggest that a firm diagnosis of Reye syndrome cannot be made without histologic examination of the liver.

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Citations

Nov 1, 1985·Indian Journal of Pediatrics·S ParekhB Agarwal
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