Acute lupus pneumonitis with normal chest radiograph

Chest
I Susanto, J I Peters

Abstract

Patients with acute lupus pneumonitis (ALP) usually have hypoxemia, patchy infiltrates evidenced on a chest x-ray film, and an incomplete response to corticosteroids with high mortality. In contrast, lupus patients with a syndrome of acute reversible hypoxemia (SARH) have hypoxemia with normal chest x-ray films and a rapid response to corticosteroids. We present a case of biopsy-proven ALP with normal initial chest x-ray films, and a normal CT scan. We hypothesize that a continuum of vascular and parenchymal abnormalities may exist in the lungs of lupus patients. This case also illustrates the insensitivity of routine chest radiographs in demonstrating mild or early pneumonitis.

Citations

Aug 25, 2000·Current Opinion in Pulmonary Medicine·G S Cheema, F P Quismorio
Sep 26, 2001·Postgraduate Medical Journal·A G RockallP J Shaw
Oct 2, 2012·Archives of Pathology & Laboratory Medicine·Frank SchneiderKevin O Leslie
Nov 7, 2002·Critical Care Clinics·Rishi RajHerbert P Wiedemann
Aug 28, 2004·Clinics in Chest Medicine·Charlie Strange, Kristin B Highland
Jun 4, 2002·Best Practice & Research. Clinical Rheumatology·Amy H Kao, Susan Manzi

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