Acute mesenteric ischemia induced by ligation of porcine superior mesenteric vein: multidetector CT evaluations

Academic Radiology
Zuo Hua TangXuan Guang Ye

Abstract

To evaluate multidetector computed tomography (MDCT) for detecting the early changes and dynamic evolution of acute mesenteric ischemia (AMI) induced by the ligation of superior mesenteric vein (SMV) in an experimental porcine model. Twelve pigs were randomly assigned to three experimental groups, and one control group with three pigs in each group. After laparotomy, the SMV was separated and ligated in nine pigs and separated without ligation in three controls. MDCT pre- and postcontrast with arterial, venous, and delayed phase scans, and CT angiography reconstructions of mesenteric vessels were carried out at preoperation, 6 hours, 12 hours, and 18 hours after ligation. The findings of mesenteric vessels, bowel, abdominal cavity at pre- and postoperation, and dynamic evolution were correlated with pathology. AMI-induced pathological changes were identified in all nine experimental pigs. MDCT angiography clearly delineated main trunk of the SMV, peripheral major and minor tributaries up to brushy vasa recta, and the location and shape of ligations. The early ischemic findings were bowel wall thickening, mesenteric edema, ascites, and pronounced bowel enhancement. Superior mesenteric artery and its major branches appeared spasm...Continue Reading

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Citations

Jan 17, 2013·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yon-Cheong WongChen-Chih Huang
Nov 22, 2014·American Journal of Physiology. Gastrointestinal and Liver Physiology·Liara M GonzalezAnthony T Blikslager
Jan 21, 2012·Journal of Computer Assisted Tomography·Maria Antonietta MazzeiLuca Volterrani

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