Abstract
Tyrosine hydroxylase (TH) mRNA levels in the rat substantia nigra (SN), ventral tegmental area (VTA) and locus coeruleus (LC) were measured by in situ hybridization histochemistry 1, 4, 6 and 24 h after a single injection of methamphetamine (MAP, 4 mg/kg, i.p.) or an equivalent volume of saline. TH mRNA levels in LC were transiently increased (130% of control saline group, P < 0.05) at 1 h after MAP injection, and returned to basal levels within 4 h. In contrast, acute MAP administration did not significantly affect TH mRNA levels in SN and VTA. These findings are the first to demonstrate TH mRNA expression in the different responses of catecholaminergic neurons to acute MAP administration.
References
Mar 1, 1979·Brain Research Bulletin·M K SangheraP A Shore
Oct 6, 1992·European Journal of Pharmacology·O CuretP Blier
Apr 24, 1992·Brain Research·Y L HurdT Hökfelt
Mar 22, 1991·Brain Research·M A SmithM Herkenham
May 14, 1990·Brain Research·X Guitart, E J Nestler
Aug 2, 1990·European Journal of Pharmacology·A L GundlachW J Louis
Oct 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·E J NestlerR S Duman
Mar 28, 1991·Nature·T PacholczykS G Amara
Jan 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·B GrimaJ Mallet
Mar 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·A BerodJ Mallet
Jun 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·E J LewisD M Chikaraishi
Aug 19, 1985·Brain Research·L J RyanP M Groves
Dec 1, 1974·European Journal of Pharmacology·M T Price, H C Fibiger
Nov 12, 1971·Nature·A W Graham, G K Aghajanian
Jul 30, 1984·Brain Research·L J PorrinoL Sokoloff
Jan 1, 1982·Psychopharmacology·L Kokkinidis, E P MacNeill
Sep 1, 1995·Neuroscience·J Q WangJ F McGinty
Sep 15, 1995·The Journal of Biological Chemistry·M LazaroffD M Chikaraishi
Dec 1, 1994·British Journal of Pharmacology·F KaroumR J Wyatt
Jan 1, 1993·Neuroreport·A M PersicoG R Uhl
Apr 1, 1993·Brain Research. Molecular Brain Research·S KapurJ J Mann
Feb 15, 1996·Nature·B GirosM G Caron
Mar 1, 1996·Psychopharmacology·M E Stockton, K Rasmussen
Feb 7, 1997·Neuroscience Letters·T ShishidoI Matsuoka
Citations
Nov 2, 2001·Brain Research·N ThirietS F Ali
Feb 7, 2014·Psychopharmacology·Natalie A Hadad, Lori A Knackstedt
Feb 6, 2007·Pharmacology, Biochemistry, and Behavior·M E PageE J Van Bockstaele
Nov 16, 2004·Annals of the New York Academy of Sciences·Joana Gomes-da-SilvaM Amélia Tavares
Jul 6, 2004·Brain Research·J Michael SalbaumGiulio Tononi
Oct 8, 2005·Neuroendocrinology·Maria T PanayotacopoulouDick Swaab
Nov 21, 2000·Annals of the New York Academy of Sciences·J Gomes-da-SilvaM A Tavares