Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China

Annals of Neurology
G M McKhannL P Jou

Abstract

In northern China, annual epidemics of acute-onset flaccid paralysis diagnosed clinically as Guillain-Barré syndrome have been recognized for at least 20 years. On the basis of an historical analysis of more than 3,200 patients, distinctive features include most cases occurring during the summer months among children and young adults, most of whom reside in rural areas. Of 90 patients with acute flaccid paralysis, 88 had a distinctive pattern that shares clinical and cerebrospinal fluid findings with demyelinating Guillain-Barré syndrome, but that differs from Guillain-Barré syndrome physiologically and pathologically. The clinical course is marked by rapidly progressive ascending tetraparesis, often with respiratory failure, but without fever, systemic illness, or sensory involvement. Cerebrospinal fluid is acellular, and elevations of protein content occur in the second or third week of illness. Electrodiagnostic studies show normal motor distal latencies and limb conduction velocities, but reduced compound muscle action potential amplitudes. Sensory nerve action potentials and, when elicitable, F waves are within the range of normal. Recovery is usually good. Autopsy studies have shown Wallerian-like degeneration of motor fi...Continue Reading

References

Dec 1, 1991·Archives of Neurology·A H Ropper
Jan 1, 1990·Annual Review of Medicine·J D England
Jan 1, 1990·Annals of Neurology·D R Cornblath
Jan 1, 1990·Annals of Neurology·A K Asbury, D R Cornblath
Jan 1, 1990·Annals of Neurology·M Alter
Jan 1, 1989·Yonsei Medical Journal·C J Coe
Jan 1, 1988·Brain & Development·H S WuW C Zhang
May 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·J B WinerR P Watkins
Dec 1, 1986·Brain : a Journal of Neurology·T E FeasbyD W Zochodne
Mar 1, 1984·Brain : a Journal of Neurology·W F Brown, T E Feasby
Dec 9, 1992·Transfusion Science·R A Hughes

❮ Previous
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Citations

Mar 1, 1996·Muscle & Nerve·T E Feasby
Feb 1, 1997·Muscle & Nerve·F G van der Meché, P A van Doorn
Feb 17, 2001·Muscle & Nerve·S KuwabaraT Hattori
Feb 1, 1994·Annals of Neurology·A J KornbergZ Jiang
Jan 1, 1995·Annals of Neurology·E ChroniR A Hughes
Apr 18, 1998·Annals of Neurology·N Yuki, K Hirata
Oct 16, 2002·Journal of Clinical Apheresis·Bruce C McLeod
Mar 1, 2002·Muscle & Nerve·Yumi SakakibaraNobuhiro Yuki
Jun 1, 1994·Muscle & Nerve·T E Feasby
Feb 1, 1995·Muscle & Nerve·H P HartungK V Toyka
Jan 1, 1996·Springer Seminars in Immunopathology·H P HartungG Giegerich
Oct 12, 2000·Indian Journal of Pediatrics·V V Vedanarayanan, V Chaudhry
Nov 15, 2007·Journal of Neurology·Clarissa Crone, Christian Krarup
Dec 7, 2011·Journal of Neurology·Nobuhiro YukiAntonino Uncini
Oct 19, 2010·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Faruk IncecikSakir Altunbasak
Apr 1, 2011·Current Allergy and Asthma Reports·Todd A HardyStephen W Reddel
Nov 30, 2000·Current Treatment Options in Neurology·C F Bolton, G B Young
Apr 12, 2013·Current Treatment Options in Neurology·Mazen M Dimachkie, Richard J Barohn
Apr 22, 2009·Indian Journal of Pediatrics·Veena KalraBenu Dhawan
Apr 1, 1996·Journal of the Neurological Sciences·V GovoniV C Monetti
Apr 1, 1996·Indian Pediatrics·S G LalwaniM K Jain
Jun 25, 2013·Cytokine & Growth Factor Reviews·Hong-Liang ZhangJie Zhu
Mar 17, 2004·Journal of Neuroimmunology·Y Y JuN A Gregson
Mar 19, 2002·Journal of the Neurological Sciences·Keiichiro SusukiSatoshi Kuwabara
Jun 27, 2002·Journal of the Neurological Sciences·Satoshi KuwabaraNobuhiro Yuki
May 28, 2003·Journal of the Neurological Sciences·Masaaki OdakaSatoshi Kuwabara
Oct 22, 2003·Journal of the Neurological Sciences·Qi ChengSten Fredrikson
Feb 12, 1997·Journal of the Neurological Sciences·A Khalili-ShiraziJ S Lanchbury
Feb 1, 2003·Survey of Ophthalmology·Michael S Vaphiades

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