Acute Myocardial Infarction Following Administration of Polyethylene Glycol Electrolyte Solution with Ascorbic Acid (MoviPrep® ) at Home: A Case Report

Drug Safety - Case Reports
Naruaki ImotoNaoyuki Hashiguchi

Abstract

A male individual aged 82 years with hypertension who had a smoking history, but no history of cardiovascular events, developed acute myocardial infarction immediately after he took oral polyethylene glycol electrolyte solution with ascorbic acid as a pretreatment for a colonoscopy to examine anemia. He took polyethylene glycol electrolyte solution with ascorbic acid at twice (2 L/h) the rate recommended in the package insert and by the physician. The patient showed impaired consciousness 2 h after taking polyethylene glycol electrolyte solution with ascorbic acid and his family called the emergency medical service. Upon arrival of the emergency medical service, his systolic blood pressure was 60 mmHg and heart rate was 50 bpm. Systolic blood pressure and impaired consciousness were slightly improved, but compensatory shock remained, at arrival at the emergency outpatient service at our hospital. No dyspnea or rash was apparent. The patient had no subjective chest pain; however, ST-segment elevation was detected in the electrocardiogram at II, III, aVF, V3R, and V4R. He was diagnosed with ST-segment elevation myocardial infarction and underwent a coronary catheter intervention for total occlusion of the right coronary artery. H...Continue Reading

References

Jun 23, 2001·The American Journal of Gastroenterology·R M NessN Chalasani
Jul 14, 2005·Annual Review of Nutrition·John X Wilson
Jan 19, 2010·Digestive Diseases and Sciences·Benjamin LebwohlAlfred I Neugut
Dec 20, 2011·World Journal of Gastroenterology : WJG·Stefano PontoneAdriano Redler
Jan 14, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Cesare HassanAlessandro Repici
Mar 16, 2013·Clinical Therapeutics·Nicholas G Kounis
Jun 19, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Thierry PonchonMarc Halphen
Feb 18, 2015·BioMed Research International·Toshihiko SagawaMasanobu Yamada

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