Acute myocardial infarction in systemic sclerosis patients: a case series

Clinical Rheumatology
Chris T Derk, Sergio A Jimenez

Abstract

To characterize the clinical manifestations of patients with systemic sclerosis who develop a myocardial infarction (MI), a retrospective review of the medical records of all patients who were admitted to our institution between 1982 and 2002 and had the dual diagnosis of systemic sclerosis and an acute MI was done. From 1,009 systemic sclerosis hospital admissions, 11 (1.09%) were for an acute MI. Three of these patients had normal coronaries, and instead of wall motion abnormalities, left ventricular hypertrophy was the predominant finding of an echocardiography. The odds ratio of finding normal coronaries in systemic sclerosis vs the general population who develops an acute MI is 33.89 (14.08-81.39). Seven of our patients had an elevated creatinine level on presentation. Acute MI is an uncommon manifestation in systemic sclerosis patients. Normal coronaries are seen more commonly in these patients as compared to the general population, while vascular, gastrointestinal, and renal involvement is prevalent in these patients.

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Citations

Sep 6, 2011·Arthritis Research & Therapy·Gene-Siew NgianSharon Van Doornum
May 31, 2014·BMJ Case Reports·Arwa AburizikChristopher Blosser
May 27, 2014·Clinical Rheumatology·Patompong UngprasertPromporn Suksaranjit
May 31, 2015·Modern Rheumatology·Patompong UngprasertSikarin Upala
Oct 26, 2013·The American Journal of Medicine·Szu-Ying ChuHan-Nan Liu
Feb 19, 2013·The American Journal of Cardiology·Dawn C ScantleburyPatricia J M Best
Jan 17, 2013·Psychosomatics·Susan McNairBruno Losier
Sep 26, 2007·Annals of the New York Academy of Sciences·Francesca BartoliMarco Matucci Cerinic
May 4, 2011·Arthritis and Rheumatism·Mo Yin MokKaren Siu Ling Lam
Apr 18, 2015·International Journal of Rheumatic Diseases·Hassan AliAndrea H L Low
Apr 25, 2014·The American Journal of Medicine·Tomoyuki Kawada
Jul 14, 2016·Rheumatology International·Antonios PsarrasTheodoros Dimitroulas
Jul 27, 2010·Current Opinion in Rheumatology·Adel BoueizPaul M Hassoun
Jan 17, 2020·British Journal of Pharmacology·Antigone LazouIoanna Andreadou
Oct 24, 2008·Current Opinion in Rheumatology

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