Acute myocardial infarction: susceptibility-weighted cardiac MRI for the detection of reperfusion haemorrhage at 1.5 T

Clinical Radiology
Giuliana DurighelDeclan P O'Regan

Abstract

To assess whether susceptibility-weighted imaging (SWI) provides better image contrast for the detection of haemorrhagic ischaemia-reperfusion injury in the heart. Thirty patients (all men; mean age 53 years) underwent cardiac magnetic resonance imaging (MRI) within 7 days of primary percutaneous intervention for acute ST elevation myocardial infarction (STEMI). Multiple gradient-echo T2* sequences with magnitude and phase reconstructions were acquired. A high-pass filtered phase map was used to create a mask for the SWI reconstructions. The difference in image contrast was assessed in those patients with microvascular obstruction. A mixed effects regression model was used to test the effect of echo time and reconstruction method on phase and contrast-to-noise ratio (CNR). Medians and interquartile ranges (IQR) are reported. T2* in haemorrhagic infarcts was shorter than in non-haemorrhagic infarcts (33.5 ms [24.9-43] versus 49.9 ms [44.6-67.6]; p=0.0007). The effect of echo time on phase was significant (p<0.0001), as was the effect of haemorrhage on phase (p=0.0016). SWI reconstruction had a significant effect on the CNR at all echo times (echoes 1-5, p<0.0001; echo 6, p=0.01; echo 7, p=0.02). The median echo number at which h...Continue Reading

References

Oct 1, 1993·Radiology·W G Bradley
Aug 31, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·E Mark HaackeJürgen R Reichenbach
Mar 1, 2005·Magnetic Resonance Imaging·E Mark HaackeAndre Obenaus
Sep 16, 2005·Journal of Magnetic Resonance Imaging : JMRI·Vivek SehgalJürgen R Reichenbach
Sep 15, 2007·The New England Journal of Medicine·Derek M Yellon, Derek J Hausenloy
Oct 9, 2007·The American Journal of Cardiology·Cristina BassoSabino Iliceto
Dec 7, 2007·The New England Journal of Medicine·Radhakrishnan Ramaraj
Sep 17, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Govind B ChavhanE Mark Haacke
Sep 24, 2011·AJR. American Journal of Roentgenology·Bronwyn E HamiltonEdward A Neuwelt
Dec 17, 2011·JACC. Cardiovascular Imaging·Andreas KumarMatthias G Friedrich
Jun 19, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·James W GoldfarbJing Han
Oct 31, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Ananth KidambiSven Plein

❮ Previous
Next ❯

Citations

May 13, 2020·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·G J H SnelN H J Prakken

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.