Acute necrotizing pancreatitis as a fatal complication following DC Bead transcatheter arterial chemoembolization for hepatocellular carcinoma: A case report and review of the literature

Molecular and Clinical Oncology
Takashi YamaguchiKazuichi Okazaki

Abstract

Transcatheter arterial chemoembolization (TACE) is one of the most effective palliative measures for patients with inoperable hepatocellular carcinoma (HCC). Acute pancreatitis is a rare but well-known complication following TACE. We herein present the case of a patient with HCC who developed fatal complications (acute necrotizing pancreatitis and upper gastrointestinal ulcers) after TACE with DC Beads. The patient was diagnosed with HCC in segments 4 and 8, measuring ~70 mm in greatest diameter, and he was treated by TACE. Hepatic arteriography revealed replacement of the origin of the right hepatic artery to the superior mesenteric artery, while the left hepatic artery originated from the celiac artery. After selection of the segmental arterial branches feeding the tumor, 2 ml of 100-300-µm-sized DC Beads loaded with 150 mg epirubicin were injected through the microcatheter. The patient complained of abdominal pain after the TACE procedure. Upper gastrointestinal endoscopy revealed longitudinal ulcers from the esophagus to the duodenum, and contrast-enhanced computed tomography revealed swelling of the pancreas and focal areas of low density in the pancreatic body, suggesting necrosis. The patient developed respiratory insuff...Continue Reading

References

Apr 24, 2007·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·R López-BenítezP J Hallscheidt
Nov 13, 2009·Cardiovascular and Interventional Radiology·Johannes LammerUNKNOWN PRECISION V Investigators
Dec 25, 2010·Cardiovascular and Interventional Radiology·Katerina MalagariDimitrios Kelekis
Jun 2, 2012·Seminars in Interventional Radiology·Mohammed Aladdin, Mohammed Ilyas
Nov 17, 2012·Clinical Imaging·Bülent KaramanGökhan Yağci
May 24, 2014·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Juan Manuel Alcívar-VásquezJuan Manuel Pascasio-Acevedo

❮ Previous
Next ❯

Citations

Jun 26, 2020·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Min Young SonJin Do Huh

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.