Acute nontraumatic splenic infarctions at a tertiary-care center: causes and predisposing factors in 123 patients

Emergency Radiology
Mougnyan CoxLaurence Needleman

Abstract

Acute splenic infarcts classically present with left upper quadrant pain, but may be discovered incidentally in many hospitalized patients with otherwise vague complaints. The purpose of our study was to document causes or predisposing conditions in patients found to have acute splenic infarctions on imaging. Following IRB approval, a retrospective review of an imaging database from May 2008 to May 2015 was performed for cases of acute splenic infarctions. The electronic medical record was then reviewed for potential predisposing factors or known causes. Specific note was made of cases with active malignancy, vascular disorders, or inflammatory conditions with an increased risk of vasculopathy. Echocardiogram and electrocardiogram results were reviewed when available. One hundred twenty-three patients with acute splenic infarcts were identified, 65 female and 58 male. The average age was 57 years (range of 22 to 88). Active malignancy was present in 40 patients or 33 %. The most common malignancy in patient with nontraumatic splenic infarctions was pancreatic cancer, present in 16 patients (13 %). In these patients, splenic infarction was due to direct invasion of vessels in the splenic hilum. Acute pancreatitis (severe) was di...Continue Reading

References

Apr 1, 1986·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R PinzonG Giacco
Dec 1, 2001·Archives of Internal Medicine·R H Thomas
Aug 17, 2004·Emergency Radiology·Orlando CatalanoAlfredo Siani
Dec 21, 2007·Emergency Radiology·Gabriela Gayer, Maya Galperin-Aizenberg
Jan 12, 2008·Emergency Radiology·Stephanie A SchwartzStephen H Smyth
Nov 30, 2010·Vascular Medicine·Saurabh SanonElie Mouhayar
Oct 4, 2011·Journal of the American College of Radiology : JACR·Vijay M RaoJonathan H Sunshine
Jan 16, 2013·Emergency Radiology·Massimo Tonolini, Roberto Bianco

❮ Previous
Next ❯

Citations

Dec 19, 2019·Emergency Medicine Journal : EMJ·Antonio J Martín-JiménezDaniel García-Gil
Jul 14, 2020·JAMA Internal Medicine·Allan S BrettMatthew A Marcus
Mar 26, 2021·Journal of Thrombosis and Thrombolysis·Jan Philipp BewersdorfAlfred Ian Lee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia Cerebrovascular Disease

Basal ganglia cerebrovascular disease is a condition where the blood vessels in the basal ganglia are damaged or malfunction. Discover the latest research on basal ganglia cerebrovascular disease here.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.