Acute onset of ulcerative colitis following an operation for sigmoid colon cancer

Journal of Gastroenterology
Mihoko TakakuraMasanori Tanaka

Abstract

We describe a case of ulcerative colitis (UC) where clinical symptoms began abruptly within a few weeks after colon resection. The patient, a 44-year-old woman, was first referred to our hospital for the treatment of colon cancer. During the past several years, she had not had any inflammatory bowel disease-like clinical symptoms, such as frequent diarrhea or abdominal discomfort. Before the operation, both macroscopic and microscopic examination revealed that no remarkable inflammatory change was associated with the cancer in any area of her colon. At 10 days after the operation, she started to complain of frequent watery diarrhea. Two weeks after the operation, she was readmitted to our hospital because of frequent bloody diarrhea, fever, and abdominal discomfort. Based on endoscopic and histological examinations, she was diagnosed as having severe UC and was treated with hyperalimentation, predonisolone, mesalazine, and granulocyte apheresis. However, she did not respond to this combination therapy. At 45 days after the first operation, owing to sudden onset hemorrhagic shock, she underwent a second colectomy. The resected specimen of the entire colon showed severe pancolitis, and histological examination revealed severe inf...Continue Reading

References

Feb 1, 1990·Gut·S A RileyS Lucas
Jul 1, 1993·Psychosomatic Medicine·T B Herbert, S Cohen
May 16, 2000·The American Journal of Gastroenterology·S LevensteinA Marcheggiano
Oct 24, 2003·The American Journal of Gastroenterology·Alain BittonSteven E Locke

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Citations

Jul 30, 2011·European Journal of Gastroenterology & Hepatology·Konstantinos H KatsanosEpameinondas V Tsianos
Nov 23, 2017·Clinical Journal of Gastroenterology·Atsuyo IkedaMasaki Mori
Jul 1, 2015·Euroasian Journal of Hepato-gastroenterology·Tuncer TemelAysegul Harmanci Ozakyol

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