PMID: 8971119Dec 1, 1996Paper

Acute oropharyngeal palsy is associated with antibodies to GQ1b and GT1a gangliosides

Journal of Neurology, Neurosurgery, and Psychiatry
C P O'LearyH J Willison

Abstract

Three patients with acute oropharyngeal palsy had high titre anti-GQ1b and anti-GT1a IgG antibodies. No patients had ophthalmoplegia or ptosis. In all patients limb ataxia or areflexia were present without notable limb weakness. These patients describe an oropharyngeal variant of Guillain-Barré syndrome in terms of anti-GQ1b antibody reactivity and show that high titre anti-GQ1b antibodies, serologically indistinguishable from those found in Miller Fisher syndrome, can occur in a clinical setting without ophthalmoplegia. The anti-GQ1b and anti-GT1a antibody assays may be helpful tests when considering the differential diagnosis of acute oropharyngeal palsy.

References

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Citations

Jul 27, 1999·Muscle & Nerve·S KusunokiI Kanazawa
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