Abstract
Pancreatic disease in patients with AIDS often is so mild that the diagnosis may be missed. The pancreas can be affected by systemic illness caused by opportunistic infections, Kaposi's sarcoma, or lymphoma. More commonly, drugs used to treat patients infected with human immunodeficiency virus can cause pancreatitis and result in significant morbidity and, rarely, mortality. We report one such case in a 47-year-old patient with AIDS in whom pancreatitis developed while taking 2',3'-dideoxyinosine (ddI). His condition improved on ddI withdrawal, but he suffered a fatal relapse while receiving 2',3'-dideoxycytidine and trimethoprim-sulfamethoxazole. This case gives me the opportunity to review the literature regarding the incidence, causes, and diagnosis of human immunodeficiency virus-associated pancreatitis.
References
May 14, 1990·The American Journal of Medicine·T F Murphy
Dec 13, 1990·The New England Journal of Medicine·M W Lambertus, R E Anderson
Feb 1, 1991·Journal of Clinical Gastroenterology·M Bonacini
May 10, 1990·The New England Journal of Medicine·J S LambertF T Valentine
Jul 1, 1990·Gastroenterology·C M WilcoxJ P Cello
Aug 1, 1990·Journal of Clinical Gastroenterology·M S Cappell, M Javeed
Jun 1, 1990·Baillière's Clinical Gastroenterology·S L Friedman
Mar 4, 1989·BMJ : British Medical Journal·B HererG Huchon
Jun 1, 1989·Digestive Diseases and Sciences·M S CappellC A Axiotis
Jul 1, 1988·Reviews of Infectious Diseases·W C BuhlesS H Koretz
Sep 5, 1987·Lancet·F BrivetJ Dormont
Aug 1, 1986·Annals of Internal Medicine·C C HawkinsD Armstrong
Jun 1, 1985·Diabetologia·D BoillotR Assan
May 29, 1993·Lancet·R JostF Salomon
Sep 1, 1994·The Annals of Pharmacotherapy·M M FoisyG D Morse
Oct 1, 1994·Baillière's Clinical Endocrinology and Metabolism·F G BrivetJ Dormont
Mar 10, 1994·The New England Journal of Medicine·D I AbramsS Kornegay
Apr 1, 1993·The Annals of Pharmacotherapy·M J SheltonG D Morse
Mar 1, 1994·The American Journal of Forensic Medicine and Pathology·S J Cina, S E Conradi
Jun 1, 1994·The Journal of Infectious Diseases·T H GraselaF T Valentine
Oct 1, 1993·Journal of Clinical Gastroenterology·M S Cappell, T Hassan
Sep 15, 1993·Annals of Internal Medicine·S L Aponte-CiprianiS Yancovitz
Sep 1, 1995·The Journal of Emergency Medicine·M T PelucioD J Ward
Oct 1, 1995·Pancreas·A G HarrisJ Delmont
Jun 1, 1996·Annals of Internal Medicine·D M Felig, M Topazian
May 1, 1996·Pancreas·E AlbuP H Gerst
Oct 1, 1996·Hematology/oncology Clinics of North America·R J Biggar, C S Rabkin
Jun 19, 1997·The New England Journal of Medicine·G P RizzardiA Lazzarin