Acute Pancreatitis and Use of Pancreatitis-Associated Drugs: A 10-Year Population-Based Cohort Study

Pancreas
Sara Bertilsson, Evangelos Kalaitzakis

Abstract

To assess the use of acute pancreatitis (AP)-associated drugs in patients with AP, the relation between sales of these drugs and the incidence of AP, and the potential impact on AP severity and recurrence. All patients with incident AP between 2003 and 2012, in a well-defined area, were retrospectively identified. Data regarding AP etiology, severity, and recurrence and use of AP-associated drugs were extracted from medical records. Drugs were classified according to an evidence-based classification system. Annual drug sales data were obtained from the Swedish drug administration service. Overall, 1457 cases of incident AP were identified. Acute pancreatitis-associated drug users increased from 32% in 2003 to 51% in 2012, reflecting increasing user rates in the general population. The incidence of AP increased during the study period but was not related to AP-associated drug user rates (P > 0.05). Recurrent AP occurred in 23% but was unrelated to AP-associated drug use (P > 0.05). In logistic regression analysis, after adjustment for comorbidity, AP-associated drug use was not related to AP severity (P > 0.05). Use of AP-associated drugs is increasingly frequent in patients with AP. However, it does not have any major impact on...Continue Reading

References

Jul 1, 1984·Gut·M Sarner, P B Cotton
Oct 1, 1995·Gut·P G LankischF Gottesleben
Sep 14, 1999·The American Journal of Gastroenterology·I A ElandB H Stricker
Jul 10, 2001·The British Journal of Surgery·B GloorM W Büchler
Nov 9, 2001·European Journal of Clinical Pharmacology·V AndersenM Andersen
Jul 24, 2002·European Journal of Clinical Pharmacology·Kerstin B BlomgrenBengt-Erik Wiholm
Sep 9, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Björn LindkvistAnders Borgström
Aug 6, 2005·Journal of Clinical Gastroenterology·Chirag D Trivedi, C S Pitchumoni
Jan 6, 2006·Alimentary Pharmacology & Therapeutics·H ThistedS P Johnsen
Mar 31, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nison BadalovScott Tenner
May 16, 2007·Journal of Clinical Psychopharmacology·Mette NørgaardHenrik Toft Sørensen
Jul 16, 2009·The American Journal of Gastroenterology·Paul Georg LankischPatrick Maisonneuve
Mar 17, 2010·Best Practice & Research. Clinical Gastroenterology·Claudia J NitscheJulia V Mayerle
May 26, 2010·Digestive Diseases and Sciences·Ilona VinklerováKarel Urbánek
Jun 29, 2011·The British Journal of Surgery·O J BakkerUNKNOWN Dutch Pancreatitis Study Group
Sep 14, 2011·The American Journal of Gastroenterology·B W Marcel SpanierMarco J Bruno
Apr 4, 2012·Annals of Surgery·Mark C van BaalUNKNOWN Dutch Pancreatitis Study Group
May 23, 2012·The American Journal of Gastroenterology·Dhiraj YadavGeorgios I Papachristou
Oct 27, 2012·Gut·Peter A BanksUNKNOWN Acute Pancreatitis Classification Working Group

❮ Previous
Next ❯

Citations

Mar 16, 2017·PloS One·Fan-Gen HsuKuang-Hsi Chang
Dec 14, 2016·The New England Journal of Medicine·Chris E ForsmarkC Mel Wilcox
Apr 22, 2017·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Sara BertilssonEvangelos Kalaitzakis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Related Papers

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Sara BertilssonEvangelos Kalaitzakis
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Qiu-ling ZhaoJing Liu
The American Journal of Gastroenterology
B W Marcel SpanierMarco J Bruno
© 2021 Meta ULC. All rights reserved