PMID: 9535236Apr 16, 1998Paper

Acute-phase neurologic complications of Haemophilus influenzae type b meningitis: association with developmental problems at school age

Journal of Child Neurology
H G TaylorR H Michaels

Abstract

The purposes of this study were to describe the incidence of acute-phase neurologic complications in a sample of 126 children with Haemophilus influenzae type b meningitis, and to determine if these complications were associated with higher rates of learning and behavior problems at school age. Risks were assessed by comparing rates of adverse psychoeducational outcomes in the 53 children in the sample with complications to corresponding outcome rates in the 67 children who were free of neurologic complications and who did not have abnormal electroencephalograms (EEGs) or computed tomographic (CT) scans. Comparisons were made by means of logistic regression analysis. Twenty-nine children (23% of the sample) had seizures, 16 (13%) were comatose or obtunded, 15 (12%) had sensorineural hearing loss, 8 (6%) had hemiparesis, and 7 (6%) had cranial nerve deficits other than hearing loss. Relative to children without complications, those with complications had higher rates of grade repetition and substandard performance on neuropsychological and achievement testing. Adverse outcomes, however, consisted primarily of more subtle cognitive and learning problems; only two of the children in the sample obtained prorated IQ scores below 70....Continue Reading

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Citations

Sep 2, 1999·Infectious Disease Clinics of North America·S L Kaplan
Apr 14, 2011·The Pediatric Infectious Disease Journal·Casper RoedNiels Obel
Dec 19, 2008·The British Journal of Clinical Psychology·L C A C VermuntE M W J Utens
Jun 18, 2002·Hospital Medicine·J M Fellick, A P J Thomson
Aug 23, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Irene KoomenMarceline van Furth
Oct 27, 2017·Italian Journal of Pediatrics·Elena BozzolaAlberto Villani

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