Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine

The Veterinary Journal
P D Eckersall, R Bell

Abstract

Acute phase proteins (APPs) have been used as biomarkers of inflammation, infection and trauma for decades in human medicine but have been relatively under-utilised in the context of veterinary medicine. However, significant progress has been made in the detection, measurement and application of APPs as biomarkers in both companion and farm animal medicine over recent years. In the dog, C-reactive protein, haptoglobin and serum amyloid A have been identified as significant diagnostic 'markers' of steroid-responsive meningitis-arteritis, while in cats and cattle haptoglobin and alpha(1) acid glycoprotein and haptoglobin and serum amyloid A have proved valuable biomarkers of disease, respectively. In dairy cattle, haptoglobin and a mammary-associated serum amyloid A3 isoform, produced by the inflamed mammary gland during episodes of mastitis, have great potential as biomarkers of this economically important disease. Understanding the use of APP as biomarkers of inflammatory conditions of domestic animals has expanded significantly over recent years, and, with the insights provided by ongoing research, it is likely that these compounds will be increasingly used in the future in the diagnosis and prognosis of both companion and far...Continue Reading

References

Oct 1, 1993·The Journal of Veterinary Medical Science·E UchidaK Takahashi
Mar 1, 1997·Research in Veterinary Science·H NakagawaN Katoh
May 27, 1999·The Veterinary Record·N U HoradagodaP D Eckersall
Oct 19, 1999·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·T A NiewoldE Gruys
Sep 30, 2000·Journal of Veterinary Internal Medicine·K A SeltingM A Scherk
Feb 24, 2001·The Veterinary Record·M Andersson, E Sevelius
Feb 24, 2001·The Veterinary Record·P D EckersallJ L Fitzpatrick
Apr 13, 2001·Journal of the American Animal Hospital Association·S S CorreaS C Mooney
Mar 28, 2002·The Veterinary Record·S Martínez-SubielaJ J Cerón
Oct 16, 2002·Animal Reproduction Science·Camila I VannucchiClair M Oliveira
May 31, 2003·Journal of Veterinary Internal Medicine·Albert E JergensRichard Evans
May 26, 2004·The Veterinary Journal·H MurataM Yoshioka
Jul 21, 2004·The Veterinary Record·S Martínez-SubielaJ J Cerón
Jan 22, 2005·Veterinary Immunology and Immunopathology·S JacobsenE Gruys
May 20, 2005·Veterinary Clinical Pathology·Jose Joaquýn CeronSilvia Martýnez-Subiela
Jul 5, 2005·Foodborne Pathogens and Disease·P TourlomoussisS Buncic
Sep 1, 2005·Veterinary Clinical Pathology·Y L McGrottyP D Eckersall
Aug 12, 2006·The Veterinary Journal·R MischkeP D Eckersall
Jan 11, 2007·The Journal of Veterinary Medical Science·Koichi OhnoHajime Tsujimoto
Feb 17, 2007·Journal of the American Veterinary Medical Association·Alexandre MerloSílvia Regina Ricci Lucas
Dec 21, 2007·BMC Veterinary Research·Peter D EckersallMichael C Fontaine
Jan 17, 2008·Journal of Veterinary Internal Medicine·Lise NielsenJoanna S Morris
Mar 6, 2008·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Angela P M VeigaFélix H D González
Mar 28, 2008·Veterinary Clinical Pathology·Alexandre MerloSílvia Regina Ricci Lucas
Jun 17, 2008·Acta Veterinaria Scandinavica·Leena SuojalaSatu Pyörälä
Jun 24, 2008·Comparative Immunology, Microbiology and Infectious Diseases·Alfonso ZecconiMassimo Amadori
Aug 12, 2008·Journal of Veterinary Internal Medicine·A Bathen-NoethenA Tipold
Sep 3, 2008·Veterinary Clinical Pathology·Goksel Bayramli, Bulent Ulutas
Oct 22, 2008·Veterinary Microbiology·H SimojokiS Pyörälä
Mar 21, 2009·Journal of Veterinary Internal Medicine·K D MitchellB Jefferson
Apr 28, 2009·Veterinary Clinical Pathology·Marta PlanellasJosep Pastor
May 29, 2009·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Ashley B SaundersJörg M Steiner
Jul 30, 2009·The Journal of Dairy Research·Gabriele GerardiSeverino Segato
Sep 18, 2009·The Journal of Dairy Research·Maria AkerstedtAse Sternesjö
Oct 14, 2009·Journal of Veterinary Emergency and Critical Care·Constance GebhardtBarbara Kohn

❮ Previous
Next ❯

Citations

Jan 24, 2014·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Carolyn CrayKristopher L Arheart
Jul 9, 2014·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Anne K H KroghMads Frost Bertelsen
May 13, 2014·Research in Veterinary Science·Katarzyna DudekEwelina Szacawa
Aug 21, 2013·The Veterinary Record·L Seppä-LassilaT Soveri
Aug 13, 2013·Research in Veterinary Science·Silvia Martínez-SubielaJose J Cerón
Mar 10, 2012·Parasites & Vectors·Viktor DyachenkoReinhard K Straubinger
Oct 4, 2012·Animal : an International Journal of Animal Bioscience·J A StrykerN A Karrow
Oct 10, 2013·The Journal of Dairy Research·Arianna MiglioCarmen Maresca
Sep 14, 2012·The Journal of Veterinary Medical Science·Hitoshi ArataniTakeo Sakai
Jan 5, 2016·Journal of Veterinary Internal Medicine·R M EichenbergerP Deplazes
Feb 7, 2016·Research in Veterinary Science·Andreia Tomás MarquesFabrizio Ceciliani
Jan 22, 2013·Veterinary Immunology and Immunopathology·Takao SegawaTakeo Sakai
Apr 29, 2014·Journal of Proteomics·Ingrid MillerElisabetta Gianazza
Jan 11, 2012·Veterinary Immunology and Immunopathology·Cristina LecchiFabrizio Ceciliani
Dec 30, 2015·The Journal of Small Animal Practice·L MacfarlaneG Mclauchlan
Jun 15, 2010·The Veterinary Journal·Ali Mobasheri, Joseph P Cassidy
Dec 17, 2015·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Matthew C AllenderCarolyn Cray
Aug 21, 2015·Journal of Veterinary Internal Medicine·M PavelskiP T Dornbusch
Sep 1, 2015·Veterinary Immunology and Immunopathology·Fabrizio CecilianiCristina Lecchi
Nov 24, 2012·The Journal of Small Animal Practice·M HestaG P J Janssens
Jul 29, 2011·Animal Science Journal = Nihon Chikusan Gakkaihō·Shiro Kushibiki
Sep 26, 2012·Veterinary Clinical Pathology·Xun TanJi-Yong Zhou
Nov 28, 2013·The Journal of Small Animal Practice·R O LealL Tavares
Jan 7, 2014·The Journal of Small Animal Practice·Peter D Eckersall, Elizabeth Moreira dos Santos Schmidt
Dec 20, 2013·Journal of Veterinary Internal Medicine·S J ViitanenM M Rajamäki

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Veterinary Journal
Saverio Paltrinieri
The Journal of Veterinary Medical Science
Masaaki NakamuraHajime Tsujimoto
European Journal of Biochemistry
C M Uhlar, A S Whitehead
© 2021 Meta ULC. All rights reserved