Acute poisoning with carbamate pesticides: the Cretan experience

Science & Justice : Journal of the Forensic Science Society
Aristidis M TsatsakisE N Michalodimitrakis

Abstract

In Crete, in southern Greece, a number of fatal carbamate poisonings were investigated over a period of 2 years, from 1991 to 1993. Five cases are reported, involving the fatal ingestion of methomyl (Lannate), a cholinesterase-inhibiting carbamate insecticide. Analysis of samples of blood plasma and serum showed more than 90% inhibition of cholinesterase. The blood methomyl concentrations had a mean value of 26.7 mg/l, and a range of 5.6-57.0 mg/l. These values are much higher than those previously reporter in similar cases (0.57-1.4 mg/l). Methomyl concentrations in organs and tissues were found to be significantly lower than those in blood and vitreous humour.

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Citations

Sep 1, 2004·Journal of Clinical Forensic Medicine·M Michalodimitrakis, A Tsatsakis
Apr 10, 2007·Therapeutic Drug Monitoring·Maria G MargaritiAristidis M Tsatsakis
Sep 24, 1998·Journal of Chromatography. B, Biomedical Sciences and Applications·S ItoN Ikeda
Mar 8, 2005·Forensic Science International : Synergy·Fumio Moriya, Yoshiaki Hashimoto
Oct 11, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Byung Kook LeeYong Hun Jung
Dec 31, 2010·Crisis·Anastasia E KastanakiManolis Michalodimitrakis
Oct 10, 2013·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·John P BuchweitzAndreas Lehner
May 2, 2003·Human & Experimental Toxicology·Maria TutudakiAristidis M Tsatsakis
Jun 6, 2002·Human & Experimental Toxicology·A M TsatsakisG N Tzanakakis
Apr 20, 1999·The American Journal of Forensic Medicine and Pathology·M MichalodimitrakisI Mouzas
Oct 16, 2018·Journal of Pineal Research·Yun-Wei PangHua-Bin Zhu
Feb 23, 2012·Seminars in Dialysis·Robert Clark SchuttMitchell H Rosner
Feb 13, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ziqiu LinShaohua Chen
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May 14, 2014·Human & Experimental Toxicology·A ZafiropoulosAm Tsatsakis
Jun 15, 1997·Analytical Chemistry·T A Brettell, R Saferstein

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