Acute pulmonary embolism on MDCT of the chest: prediction of cor pulmonale and short-term patient survival from morphologic embolus burden

AJR. American Journal of Roentgenology
C EngelkeK Marten

Abstract

To predict cor pulmonale and short-term outcome in patients with pulmonary embolism (PE), we retrospectively investigated three morphology-based MDCT systems for scoring pulmonary artery obstruction. Eighty-nine consecutive patients (51 men and 38 women; age range, 23-83 years; median, 63.3 years) with an MDCT diagnosis of acute PE were included in the study. Sixty-four patients had a coexisting malignancy. PE severity was assessed by two masked observers using three percentage arterial obstruction indexes: two severity scores adapted from conventional angiography (excluding and including arterial branch obstruction grading: scores A and B, respectively) and a CT-derived severity score (index C). Echocardiographic reports were reviewed for elevation of right ventricular pressure. Obstruction index results were analyzed for correlation with pulmonary artery pressures and for prediction of cor pulmonale and 30-day survival. Statistical analysis included kappa, analysis of variance, linear correlation, chi-square, and logistic regression tests. Kappa values of 0.89, 0.82, and 0.78 were obtained for interobserver agreement on PE severity for indexes A, B, and C, respectively. PE severity was moderate but varied significantly betwee...Continue Reading

References

Apr 1, 1992·Chest·C G Elliott
Sep 1, 1987·AJR. American Journal of Roentgenology·M F QuinnJ D Garnic
Dec 1, 1986·American Heart Journal·W KasperH Just
Jan 1, 1973·Circulation·M A StefadourosE Craige
Sep 1, 1971·The American Journal of Cardiology·K M McIntyre, A A Sasahara
Nov 1, 1995·AJR. American Journal of Roentgenology·M Remy-JardinJ P Beregi
Jan 1, 1995·Chest·S Z Goldhaber
Jun 2, 1998·Journal of Computer Assisted Tomography·A B Van RossumG J Kieft
Aug 12, 1998·International Journal of Cardiology·P MalhotraB K Sharma
Aug 26, 1998·International Journal of Cardiology·S Z Goldhaber
Aug 10, 1999·Internal Medicine·S Z Goldhaber
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·E M BaileJ R Mayo
Aug 1, 2000·AJR. American Journal of Roentgenology·M Remy-JardinA Duhamel
Jun 12, 2003·Radiologic Clinics of North America·Martine Remy-JardinJacques Remy
Jul 2, 2003·European Radiology·D CollombG Ferretti
Dec 6, 2003·Circulation·Samuel Z Goldhaber, C Gregory Elliott
Jun 10, 2004·The Journal of Trauma·David J SchultzJohn Weigelt

❮ Previous
Next ❯

Citations

Sep 25, 2008·Journal of Medical Imaging and Radiation Oncology·J K HoangO F Hennessy
Apr 22, 2011·International Journal of Clinical Practice. Supplement·S K Venkatesh
Nov 2, 2011·International Journal of Clinical Practice. Supplement·P ApfaltrerJ W Nance
May 22, 2008·AJR. American Journal of Roentgenology·Rathan M SubramaniamNoel Karalus
Sep 23, 2010·AJR. American Journal of Roentgenology·Halil DoganAlbert de Roos
Feb 24, 2011·AJR. American Journal of Roentgenology·Alessandro FurlanKyongtae T Bae
Nov 26, 2013·Radiologic Clinics of North America·Martine Remy-JardinJacques Remy
Nov 27, 2015·The British Journal of Radiology·Andreas Gunter BachAlexey Surov
Sep 7, 2012·The American Journal of Cardiology·Kelly M Chin, Gerry Coghlan
Apr 21, 2010·European Journal of Radiology·Anne-Line MoroniGilbert R Ferretti
Nov 3, 2010·Journal of Thrombosis and Haemostasis : JTH·G AviramO Rogowski
Feb 15, 2015·The American Journal of Medicine·Felix G MeinelFabian Bamberg
Dec 10, 2014·European Journal of Radiology·Andreas Gunter BachAlexey Surov
May 25, 2012·AJR. American Journal of Roentgenology·Michael F MorrisPhilip A Araoz
Sep 12, 2013·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Chunran Tong, Zhonghe Zhang
Jan 15, 2015·Journal of Computer Assisted Tomography·Mehmet Mahir AtasoySinan Şahin
Apr 27, 2019·Frontiers in Cardiovascular Medicine·David C RotzingerSalah D Qanadli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.