Jan 1, 1976

Acute renal effects of new beta-adrenergic receptor site blocking agents on renal function

Proceedings of the European Dialysis and Transplant Association
P ZechJ Traeger


The effects of two new beta blockers on renal function have been studied. There were significant decreases in urine flow, urea clearance, sodium and chloride excretion rates after acute administration. Fractional excretion of sodium (FeNa) fell significantly but did not continue to fall during chronic administration. Blood pressure and plasma renin activity decreased significantly after two months' therapy. These findings suggest that beta blockers in patients with unstable cardiovascular function increase the need for concomitant diuretic therapy.

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Mentioned in this Paper

Chloride Ion Level
Kidney Function Tests
Measurement of Fractional Excretion of Sodium
Aminohippuric Acids
Glomerular Filtration Rate
Body Excretions
Hypertensive Disease

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