Acute renal failure due to leukemic cell infiltration followed by relapse at multiple extramedullary sites in a child with acute lymphoblastic leukemia

Leukemia & Lymphoma
Atsushi SatoKazuie Iinuma

Abstract

Acute renal failure due to leukemic infiltration into the kidney is rare in childhood acute lymphoblastic leukemia (ALL). We report here a five year-old boy with ALL who presented acute renal failure caused by leukemic infiltration at onset. Treatment with predonisolone and hemodialysis was effective. However, he showed persistent or repeated relapses at extramedullary sites, such as central nervous system, testis, and pancreas, suggesting that leukemic cells of this patient may have had a high affinity to extramedullary organs. On the basis of previous reports and the experience of this patient, intensive treatment may be needed in ALL children with renal involvement.

References

Jan 1, 1988·The American Journal of Pediatric Hematology/oncology·J P NegliaM E Nesbit
Jan 1, 1986·The American Journal of Pediatric Hematology/oncology·J RajantieM A Siimes
Sep 1, 1985·The British Journal of Radiology·S Gupta, S Keane
Jan 1, 1982·Medical and Pediatric Oncology·G A TaylorB G Leventhal
Dec 18, 2001·Medical and Pediatric Oncology·S W DahlbeckR Cooper

❮ Previous
Next ❯

Citations

Feb 2, 2008·Pediatric Radiology·Melissa A HilmesPeter J Strouse
Jun 11, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ifeoma C Anochie, Felicia U Eke
Jan 26, 2007·Nature Clinical Practice. Nephrology·William M SuhMinhtri K Nguyen
Jan 8, 2008·Journal of Pediatric Hematology/oncology·Baris MalboraNamik Ozbek
Jan 6, 2010·Journal of Pediatric Hematology/oncology·Aliva De, Jill S Menell
Oct 22, 2014·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Subramaniyan RamanathanNiranjan Khandelwal
Aug 3, 2011·Radiologic Clinics of North America·R Paul GuillermanBruce R Parker
Sep 7, 2016·Pediatrics International : Official Journal of the Japan Pediatric Society·Erika BiroTamás Szabó
Feb 1, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yasuhiro IkawaRie Kuroda
Jun 8, 2019·Pediatrics International : Official Journal of the Japan Pediatric Society·Toshihiro FujikiAkihiro Yachie

❮ Previous
Next ❯

Related Concepts

Related Feeds

CNS Lymphoma

In CNS lymphoma, cancerous cells from lymph tissues or other parts of the body form tumors in the brain and/or spinal cord. Here is the latest research on this rare non-Hodgkin lymphoma.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

Nature Clinical Practice. Nephrology
William M SuhMinhtri K Nguyen
Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
Ela ErdemZ Yildiz Yildirmak
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Patricia Seo-MayerGilbert W Moeckel
© 2021 Meta ULC. All rights reserved