PMID: 16509459Mar 3, 2006Paper

Acute renal failure following liver transplantation with induction therapy

Clinical Nephrology
J GuitardL Rostaing

Abstract

To identify the predictive factors for acute renal failure (ARF) in a retrospective study of 100 orthotopic liver transplantations (OLT) performed in 94 patients between 2000 and 2003. Acute renal failure (ARF) was defined using the RIFLE criteria, i.e. injury when creatinine doubles or GFR halves, and failure when creatinine trebles or GFR decreases by > 75%. Patients on dialysis pre OLT (n = 3) were excluded from the study. Immunosuppression included steroids, calcineurin inhibitors (CNIs), with (n = 32) or without mycophenolate mofetil. A total of 85% of patients also received induction therapy with antithymocyte globulins (29%) or anti-CD25 monoclonal antibodies (56%). 39 patients (41.5%) and 21 (22.3%) patients developed injury, and failure, respectively. Of these, 10 (10.6%) underwent dialysis. Univariate analysis revealed that acute renal dysfunction with a RIFLE score > or = 3 was significantly associated with a pre-operative serum creatinine level of > 100 micromol/l, pre-operative creatinine clearance of < 75 ml/mn, need for a transfusion (> 10 red packed units), post-operative diuresis of < 100 ml/h, use of vasopressive drugs, times to aspartate (AST) and alanine (ALT) aminotransferase peaks of > 20 and > 24 hours, r...Continue Reading

Citations

Jun 24, 2009·Intensive Care Medicine·Michael JoannidisPhilipp G H Metnitz
Sep 13, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Antoine G SchneiderRinaldo Bellomo
Jun 22, 2007·Critical Care Medicine·Marlies Ostermann, René W S Chang
Apr 11, 2008·Critical Care Medicine·Eric A J Hoste, Marie Schurgers
Apr 11, 2007·Current Opinion in Nephrology and Hypertension·Sushrut S WaikarGlenn M Chertow
Feb 22, 2013·BMC Nephrology·Roberto Camargo NarcisoMarcelino Souza Durão
Aug 30, 2008·Critical Care : the Official Journal of the Critical Care Forum·José António LopesMateus Martins Prata
Jan 17, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Andrew J SimsN Suren Kanagasundaram
Aug 15, 2014·American Journal of Surgery·Lisa M McElroyDaniela P Ladner
May 9, 2012·Revista española de anestesiología y reanimación·B Alonso MenárguezJ García Fernández
Nov 26, 2010·Transplantation Proceedings·M ZhuY Yan
Oct 28, 2009·Transplantation Proceedings·A RymarzM Krawczyk
Apr 29, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Connie L Davis
Oct 31, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ashokkumar JainMark Orloff
Jan 18, 2012·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mitra K NadimRick Selby
Mar 19, 2014·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mitra K NadimYuri S Genyk
Jan 28, 2010·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Chung-Shun WongYung-Chang Chen
Sep 12, 2009·Clinical Transplantation·Ana Carina FerreiraEduardo Barroso
Dec 19, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J V GuarreraJ C Emond
Dec 15, 2010·Journal of Hepatology·C Duvoux, G P Pageaux
Jan 27, 2017·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ina JochmansJacques Pirenne
Apr 21, 2009·Lancet·John W Pickering, Zoltan H Endre
Mar 25, 2016·World Journal of Transplantation·Patricia WiesenPierre Damas
Jun 30, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Thomas SolimanGabriela A Berlakovich
Jun 23, 2009·Shock·Chih-Hsiang ChangChih-Wei Yang
Nov 18, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A O'RiordanA J Watson
Nov 2, 2006·Current Opinion in Critical Care·Eric A J Hoste, John A Kellum
Aug 8, 2008·Current Opinion in Organ Transplantation·Gianni Biancofiore, Connie L Davis
Mar 14, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Sushrut S WaikarGlenn M Chertow
Sep 25, 2010·Renal Failure·Elizabeth M MooreD James Cooper
Nov 30, 2016·World Journal of Gastroenterology : WJG·Ilaria UmbroAnna Paola Mitterhofer
Apr 11, 2013·Critical Care Research and Practice·James CaseAkram Khan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Related Papers

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
N SinghMarilyn M Wagener
Critical Care : the Official Journal of the Critical Care Forum
Ravindra L MehtaAcute Kidney Injury Network
Critical Care Medicine
Marlies Ostermann, René W S Chang
© 2021 Meta ULC. All rights reserved